Rabbit Anti-ASCL1 Recombinant Antibody (VS13-YC70) (CAT#: VS13-YC70)
The Rabbit Anti-ASCL1 Recombinant Antibody is specific for human ASCL1. ASCL1, a basic helix-loop-helix transcription factor, is crucial for neuronal differentiation, with mutations potentially contributing to congenital hypoventilation syndrome, and requiring dimerization for DNA binding. The anti-ASCL1 antibody can be used for Immunohistochemistry (1/100-1/200).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg
Figure 2 High expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg
Figure 3 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg
Figure 5 RNA cell line category: Group enriched (SCLC-21H, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
Specifications
- Immunogen
- Recombinant human MASH1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ASCL1
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Achaete-Scute Family BHLH Transcription Factor 1; Class A Basic Helix-Loop-Helix Protein 46; BHLHa46; ASH-1; HASH1; ASH1; Achaete-Scute Complex (Drosophila) Homolog-Like 1; Achaete-Scute Complex Homolog 1 (Drosophila);
- Gene ID
- 429
- UniProt ID
- P50553
- Long Name
- Achaete-Scute Family BHLH Transcription Factor 1
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1209CT | Mouse Anti-ASCL1 Recombinant Antibody (clone EML200) | WB | Mouse IgG2a |
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