Rabbit Anti-ASCL1 Recombinant Antibody (VS13-YC70) (CAT#: VS13-YC70)
The Rabbit Anti-ASCL1 Recombinant Antibody is specific for human ASCL1. ASCL1, a basic helix-loop-helix transcription factor, is crucial for neuronal differentiation, with mutations potentially contributing to congenital hypoventilation syndrome, and requiring dimerization for DNA binding. The anti-ASCL1 antibody can be used for Immunohistochemistry (1/100-1/200).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76307/1796_F10_5_selected.jpg
Figure 2 High expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/ihc_selected.jpg
Figure 3 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_A_1_3_val_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29217/62863_B_8_5.jpg
Figure 5 RNA cell line category: Group enriched (SCLC-21H, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139352-ASCL1
Specifications
- Immunogen
- Recombinant human MASH1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ASCL1
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Achaete-Scute Family BHLH Transcription Factor 1; Class A Basic Helix-Loop-Helix Protein 46; BHLHa46; ASH-1; HASH1; ASH1; Achaete-Scute Complex (Drosophila) Homolog-Like 1; Achaete-Scute Complex Homolog 1 (Drosophila);
- Gene ID
- 429
- UniProt ID
- P50553
- Long Name
- Achaete-Scute Family BHLH Transcription Factor 1
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1209CT | Mouse Anti-ASCL1 Recombinant Antibody (clone EML200) | WB | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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