AbPlus™ Anti-ATIC Magnetic Beads (VS-0724-YC890) (CAT#: VS-0724-YC890)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-ATIC specific antibody

• Target
• ATIC

• Immunogen
• Recombinant human ATIC fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]

• Alternative Names
• 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase; PURH; 5-Aminoimidazole-4-Carboxamide-1-Beta-D-Ribonucleotide Transformylase/Inosinicase; AICAR Formyltransferase/IMP Cyclohydrolase Bifunctional Enzyme; Epididymis Secretory Sperm Binding Protein Li 70p; Bifunctional Purine Biosynthesis Protein PURH;

• Gene ID
• 471

• UniProt ID
• P31939

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