Human Anti-B2M Recombinant Antibody (clone B2M-1D8) (CAT#: HPAB-0130-FY)

Recombinant monoclonal antibody to B2M. This product is a recombinant humanized antibody that recognizes human B2M. The antibody B2M-1D8 reacts with the the epitope (C-terminus) of B2M.


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  • Published Data
  • Gene Expression
  • Datasheet
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ELISA

Figure 1 ELISA result, proves that selected B2M antibodies specific ground suppresses combining of B2M antibody (B2) and B2M.

Figure 1 ELISA result, proves that selected B2M antibodies specific ground suppresses combining of B2M antibody (B2) and B2M.

FC

Figure 2 Flow cytometer result, confirms that selected B2M antibody combines with the B2M specificity of tumor cell surface.

Figure 2 Flow cytometer result, confirms that selected B2M antibody combines with the B2M specificity of tumor cell surface.

FC

Figure 3 The flow cytometer result, proves that selected B2M antibody can be at external evoked apoptosis of tumor cells.

Figure 3 The flow cytometer result, proves that selected B2M antibody can be at external evoked apoptosis of tumor cells.

Fig. A shows the tumour cell of apoptosis for Annexin V dyeing.Fig. B is the result that TUNEL measures.

FC

Figure 4 The flow cytometer result, proves that selected B2M antibody can be at external evoked former generation cloak cell lymphoma cell apoptosis.

Figure 4 The flow cytometer result, proves that selected B2M antibody can be at external evoked former generation cloak cell lymphoma cell apoptosis.

Figure 5 Selected B2M antibody does not cause apoptosis external to normal blood cell (comprising PMBC, CD3+T cell, CD16+NK cell and CD19+B cell).

Figure 5 Selected B2M antibody does not cause apoptosis external to normal blood cell (comprising PMBC, CD3+T cell, CD16+NK cell and CD19+B cell).

FC

Figure 6 The flow cytometer result, proves that humanization B2M antibody can be at external evoked apoptosis of tumor cells.

Figure 6 The flow cytometer result, proves that humanization B2M antibody can be at external evoked apoptosis of tumor cells.

FC

Figure 7 Flow cytometer result has shown that humanization B2M antibody can suppress mouse source B2M antibody and combine with the B2M of tumor cell surface, proves that the humanization B2M antibody that is obtained can combine with the B2M specificity.

Figure 7 Flow cytometer result has shown that humanization B2M antibody can suppress mouse source B2M antibody and combine with the B2M of tumor cell surface, proves that the humanization B2M antibody that is obtained can combine with the B2M specificity.


Specifications

  • Immunogen
  • Mouse spleen cells with SP2 / 0 myeloma cells by three B2M immunized BALB under action of PEG2000, B2M using antigen-coated indirect ELISA screening anti-B2M antibody positive secreting hybridomas.
  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized IgG1, λ
  • Specificity
  • Human B2M
  • Species Reactivity
  • Human
  • Clone
  • B2M-1D8
  • Applications
  • ELISA, FC
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Flow Cytometry.

Target

  • Alternative Names
  • Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone B2M-1D8"

See other products for "B2M"

Single-domain Antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-1010MZ Chicken Anti-beta-2 Microglobulin Polyclonal IgY WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-034CQ Mouse Anti-B2M Recombinant Antibody (clone YTH470.5) FC, Block Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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