AbPlus™ Anti-Bax Magnetic Beads (VS-0724-YC93)

CAT#: VS-0724-YC93

The AbPlus Anti-Bax Magnetic Beads (VS-0724-YC93) is an innovative affinity resin which is bound with anti-Bax specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of Bax protein under native and denaturing conditions.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Colon Figure 3 Liver Figure 4 Kidney Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Low cell line specificity

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-Bax specific antibody
  • Target
  • Bax
  • Immunogen
  • Synthetic peptide corresponding to the center region of the mouse BAX.
  • Target Species
  • Mouse
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • Enables Hsp70 protein binding activity; chaperone binding activity; and identical protein binding activity. Involved in activation of cysteine-type endopeptidase activity involved in apoptotic process. Acts upstream of or within several processes, including animal organ development; apoptotic signaling pathway; and regulation of apoptotic process. Located in cytosol; endoplasmic reticulum; and mitochondrial outer membrane. Part of BAX complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; colorectal cancer; and lung non-small cell carcinoma. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).
  • Alternative Names
  • BCL2 Associated X, Apoptosis Regulator; BCL2 Associated X Protein; Bcl-2-Like Protein 4; Bcl2-L-4; BCL2L4; BCL2-Associated X Protein Omega;
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