CytoStream™ Rabbit Anti-BAX Recombinant Antibody (VS13-YC89)
CAT#: VS13-YC89
The CytoStream™ Rabbit Anti-BAX Recombinant Antibody is specific for human, mouse and rat BAX. BAX, part of the BCL2 family, acts as an apoptotic activator via dimerization, promoting mitochondrial membrane potential loss, with expression influenced by p53 and splicing variants found. The anti-BAX antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX
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Specifications
- Immunogen
- Recombinant human Bax, aa 1-50.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat BAX
- Species Reactivity
- Human, Mouse, Rat, Chicken (Predicted), Goat (Predicted), Pig (Predicted)
- Applications
- WB, IF, FC, IP
- Conjugate
- NONE
- Related Disease
- Colorectal Cancer; T-Cell Acute Lymphoblastic Leukemia
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/5000
Immunofluorescence (IF): 1/100
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- BCL2 Associated X, Apoptosis Regulator; BCL2 Associated X Protein; Bcl-2-Like Protein 4; Bcl2-L-4; BCL2L4; BCL2-Associated X Protein Omega;
- Gene ID
- 581
- UniProt ID
- Q07812
- Long Name
- BCL2 Associated X, Apoptosis Regulator
- Cellular Localization
- Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleus
- Protein Refseq
- NP_001278357.1; XP_047295124.1
- Function
- Plays a role in the mitochondrial apoptotic process. Promotes activation of CASP3, and thereby apoptosis.
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Related Diseases
Breast Cancer
Endometrial Cancer
Gastric Cancer
Prostate Cancer
Throid Cancer
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Amyotrophic Lateral Sclerosis
Related Signaling Pathways
p53 Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "BAX"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B001(A) | Recombinant Anti-human BaX Intrabody [(D-Arg)9] | ELISA, ICC, FuncS | vhh-(D-Arg)9 |
| IAB-B001(G) | Recombinant Anti-human BaX Intrabody [+36GFP] | PCA, Neut, FuncS | vhh-(+36GFP) |
| IAB-B001(T) | Recombinant Anti-human BaX Intrabody [Tat] | WB, Neut, FuncS | vhh-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0056CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0056CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0057CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0057CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0058CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0058CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0059CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0059CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0060CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0060CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0900MZ | Mouse Anti-BAX Recombinant Antibody (clone 6A7) | IHC-P | Mouse IgG1 |
| HPAB-2973LY | Human Anti-BAX Recombinant Antibody (HPAB-2973LY) | Inhib, ELISA | Human IgG |
| HPAB-2974LY | Human Anti-BAX Recombinant Antibody (HPAB-2974LY) | ELISA, Inhib | Human IgG |
| ZG-0326F | Mouse Anti-BAX Recombinant Antibody (ZG-0326F) | WB | Mouse IgG |
| ZG-0370U | Rabbit Anti-BAX Recombinant Antibody (clone G26-R) | ELISA, WB, IP, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-038CQ | Mouse Anti-BAX Recombinant Antibody (clone 2D2) | WB, IP, FC, IHC, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0328 | Hi-Affi™ Rabbit Anti-BAX Recombinant Antibody (clone DS328AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-255 | Rat Anti-BAX Recombinant Antibody (clone 3C10); scFv Fragment | ELISA, WB, Inhib | Rat scFv |
| HPAB-2961LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2961LY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-2962LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2962LY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-2963LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2963LY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-2964LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2964LY-S(P)) | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2961LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2961LY-F(E)) | ELISA, Inhib | Human Fab |
| HPAB-2962LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2962LY-F(E)) | ELISA, Inhib | Human Fab |
| HPAB-2963LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2963LY-F(E)) | ELISA, Inhib | Human Fab |
| HPAB-2964LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2964LY-F(E)) | ELISA, Inhib | Human Fab |
| HPAB-2965LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2965LY-F(E)) | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC93 | AbPlus™ Anti-Bax Magnetic Beads (VS-0724-YC93) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY47 | Mouse Anti-NHP BAX Recombinant Antibody (clone 2D2) | WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY225 | Anti-BAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY699 | Anti-Mouse BAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY698 | Anti-Human BAX Immunohistochemistry Kit | IHC |
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