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    CytoStream™ Rabbit Anti-BAX Recombinant Antibody (VS13-YC89) (CAT#: VS13-YC89)

    The CytoStream™ Rabbit Anti-BAX Recombinant Antibody is specific for human, mouse and rat BAX. BAX, part of the BCL2 family, acts as an apoptotic activator via dimerization, promoting mitochondrial membrane potential loss, with expression influenced by p53 and splicing variants found. The anti-BAX antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Low cell line specificity
    Figure 7 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX

    Specifications

    • Immunogen
    • Recombinant human Bax, aa 1-50.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse and Rat BAX
    • Species Reactivity
    • Human, Mouse, Rat, Chicken (Predicted), Goat (Predicted), Pig (Predicted)
    • Applications
    • WB, IF, FC, IP
    • Conjugate
    • NONE
    • Related Disease
    • Colorectal Cancer; T-Cell Acute Lymphoblastic Leukemia

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/500-1/5000
      Immunofluorescence (IF): 1/100
      Flow cytometry (FC): 1/50-1/100

    Target

    • Alternative Names
    • BCL2 Associated X, Apoptosis Regulator; BCL2 Associated X Protein; Bcl-2-Like Protein 4; Bcl2-L-4; BCL2L4; BCL2-Associated X Protein Omega;
    • Long Name
    • BCL2 Associated X, Apoptosis Regulator
    • Cellular Localization
    • Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane; Nucleus
    • Function
    • Plays a role in the mitochondrial apoptotic process. Promotes activation of CASP3, and thereby apoptosis.

    Recommended Products

    Secondary Antibody

    Isotype Control

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "BAX"

    Select a product category from the dropdown menu below to view related products.
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    CAT Product Name Application Type
    MOB-101-S(P) Recombinant Anti-human BAX Antibody scFv Fragment ELISA, IF, FuncS scFv
    MHH-101-S(P) Recombinant Human Anti-human BAX Antibody scFv Fragment WB, Neut, FuncS scFv
    PSBC-255 Rat Anti-BAX Recombinant Antibody (clone 3C10); scFv Fragment ELISA, WB, Inhib Rat scFv
    HPAB-2961LY-S(P) Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2961LY-S(P)) ELISA, Inhib Human scFv
    HPAB-2962LY-S(P) Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2962LY-S(P)) ELISA, Inhib Human scFv

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