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    Mouse Anti-BCAP31 Recombinant Antibody (VS3-CJ1018) (CAT#: VS3-CJ1018)

    This product is a mouse antibody that recognizes human BCAP31.

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    • Conjugation:

    • Endotoxin:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15350/if_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human pancreas
    Figure 3 IHC staining of human pancreas
    (Immunohistochemical staining of human pancreas shows cytoplasmic positivity in exocrine glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/15350/ihc_selected.jpg
    Figure 4 Testis
    Figure 4 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_5_6.jpg
    Figure 5 Lymph node
    Figure 5 Lymph node
    (Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_9_8.jpg
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_B_8_5.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_7_3.jpg
    Figure 8 Liver
    Figure 8 Liver
    (Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_8_4.jpg
    Figure 9 Kidney
    Figure 9 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_9_5.jpg
    RNA Expression
    Figure 10 RNA cell line category: Low cell line specificity
    Figure 10 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185825-BCAP31

    Specifications

    • Immunogen
    • Recombinant protein of BCAP31
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1, κ
    • Specificity
    • Human BCAP31
    • Species Reactivity
    • Human
    • Applications
    • WB, IHC
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Protein A/G affinity purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • PBS, pH 7.3.
    • Preservative
    • 0.09% Sodium Azide
    • Storage
    • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been tested for use in Western Blot (1:2000), Immunohistochemistry (1:25).

    Target

    • Alternative Names
    • CDM; DDCH; BAP31; 6C6-AG; DXS1357E
    • Sequence Similarities
    • Belongs to the BCAP29/BCAP31 family.
    • Cellular Localization
    • Endoplasmic reticulum, Membrane
    • Post Translation Modifications
    • Cleaved by CASP8 and other caspases.
    • Function
    • Functions as a chaperone protein (PubMed:9396746, PubMed:18287538).
      Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746, PubMed:18287538).
      Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746, PubMed:18287538).
      Also serves as a cargo receptor for the export of transmembrane proteins (By similarity).
      Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022).
      In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022).
      May be involved in CASP8-mediated apoptosis (PubMed:10958671).

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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "BCAP31"

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    CAT Product Name Application Type
    MOB-2978z Mouse Anti-BCAP31 Recombinant Antibody (clone 35H7) WB, ELISA Mouse IgG1, κ
    MOB-0676MZ Mouse Anti-BCAP31 Recombinant Antibody (clone 8B4CC7) FC, IP, WB Mouse IgG1
    MRO-0154-CN Rabbit Anti-BCAP31 Recombinant Antibody (clone JG37-81) WB, IF, IHC, FC Rabbit IgG
    VS4-WK46 Rabbit Anti-BCAP31 Recombinant Antibody (clone 12G12) ELISA, WB, IHC, IF, FC Rabbit IgG
    VS3-FY2631 Mouse Anti-BCAP31 Recombinant Antibody (VS3-FY2631) WB, IHC Mouse IgG

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