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  • Mouse Anti-BCAP31 Recombinant Antibody (VS3-CJ1018)

Mouse Anti-BCAP31 Recombinant Antibody (VS3-CJ1018) (CAT#: VS3-CJ1018)

This product is a mouse antibody that recognizes human BCAP31.


See more Engineered Antibody products for BCAP31
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  • Gene Expression
  • Datasheet
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  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/if_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15350/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human pancreas
Figure 3 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows cytoplasmic positivity in exocrine glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15350/ihc_selected.jpg
Figure 4 Testis
Figure 4 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_5_6.jpg
Figure 5 Lymph node
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_9_8.jpg
Figure 6 Cerebral cortex
Figure 6 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_B_8_5.jpg
Figure 7 Colon
Figure 7 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_7_3.jpg
Figure 8 Liver
Figure 8 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_8_4.jpg
Figure 9 Kidney
Figure 9 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3906/11734_A_9_5.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185825-BCAP31

Specifications

  • Immunogen
  • Recombinant protein of BCAP31
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Human BCAP31
  • Species Reactivity
  • Human
  • Applications
  • WB, IHC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Protein A/G affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.3.
  • Preservative
  • 0.09% Sodium Azide
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Western Blot (1:2000), Immunohistochemistry (1:25).

Target

  • Alternative Names
  • CDM; DDCH; BAP31; 6C6-AG; DXS1357E
  • Sequence Similarities
  • Belongs to the BCAP29/BCAP31 family.
  • Cellular Localization
  • Endoplasmic reticulum, Membrane
  • Post Translation Modifications
  • Cleaved by CASP8 and other caspases.
  • Function
  • Functions as a chaperone protein (PubMed:9396746, PubMed:18287538).
    Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746, PubMed:18287538).
    Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746, PubMed:18287538).
    Also serves as a cargo receptor for the export of transmembrane proteins (By similarity).
    Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022).
    In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022).
    May be involved in CASP8-mediated apoptosis (PubMed:10958671).

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Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "BCAP31"

Recombinant Antibody

CAT Product Name Application Type
MOB-2978z Mouse Anti-BCAP31 Recombinant Antibody (clone 35H7) WB, ELISA Mouse IgG1, κ
MOB-0676MZ Mouse Anti-BCAP31 Recombinant Antibody (clone 8B4CC7) FC, IP, WB Mouse IgG1
MRO-0154-CN Rabbit Anti-BCAP31 Recombinant Antibody (clone JG37-81) WB, IF, IHC, FC Rabbit IgG
VS4-WK46 Rabbit Anti-BCAP31 Recombinant Antibody (clone 12G12) ELISA, WB, IHC, IF, FC Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0336 Hi-Affi™ Rabbit Anti-BCAP31 Recombinant Antibody (clone DS336AB) FC, IF, IHC-P, WB Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN0401 PE-A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer FCM, IHC
MHC-CN0402 APC-A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer FCM, IHC
MHC-CN0403 FITC-A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer FCM, IHC
MHC-CN0404 A*02:01/Human BCAP31 (KLDVGNAEV) MHC Tetramer FCM, IHC

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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