Mouse Anti-BCAP31 Recombinant Antibody (VS3-FY2631)

CAT#: VS3-FY2631

The anti-BCAP31 product is a recombinant mouse monoclonal antibody that binds to BAP31 protein, a calculated weight of 30.0 kDa. It shows capability of cross-reacting with human and mouse. The monoclonal antibody can be used in the area of Deafness, Dystonia, and Cerebral Hypomyelination and Adrenoleukodystrophy. This monoclonal antibody can be used in Western Blot, Immunohistochemistry.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IF staining of human cell line A-431 Figure 3 IHC staining of human pancreas Figure 4 Testis Figure 5 Lymph node Figure 6 Cerebral cortex Figure 7 Colon Figure 8 Liver Figure 9 Kidney Figure 10 RNA cell line category: Low cell line specificity

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • B cell receptor associated protein 31 of human and mouse origins
  • Species Reactivity
  • Human, Mouse
  • Applications
  • WB, IHC
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 30.0 kDa.
  • Related Disease
  • Deafness, Dystonia, And Cerebral Hypomyelination and Adrenoleukodystrophy

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/2000
    Immunohistochemistry: 1/50-1/200

Target

  • Alternative Names
  • B Cell Receptor Associated Protein 31; C6-AG Tumor-Associated Antigen; DXS1357E; BAP31; B-Cell Receptor-Associated Protein 31; B-Cell Receptor Associated Protein 31; BCR-Associated Protein Bap31; BCR-Associated Protein 31
  • Sequence Similarities
  • Belongs to the BCAP29/BCAP31 family.
  • Cellular Localization
  • Endoplasmic reticulum membrane; Multi-pass membrane protein
    Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein
  • Post Translation Modifications
  • Cleaved by CASP8 and other caspases.
    Ubiquitination at Lys79, Lys95, Lys149, Lys158, Lys159, Lys167, Lys185, and Lys204
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
  • Function
  • Functions as a chaperone protein (PubMed:9396746, 18287538).
    Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746, 18287538).
    Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746, 18287538).
    Also serves as a cargo receptor for the export of transmembrane proteins (By similarity).
    Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Secondary Antibody

Isotype Control

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