Rabbit Anti-BCL2L11 Recombinant Antibody (VS13-YC98)
CAT#: VS13-YC98
The Rabbit Anti-BCL2L11 Recombinant Antibody is specific for human and mouse BCL2L11. BCL2L11, a BCL-2 family member, interacts with other family proteins to induce apoptosis, influenced by factors like nerve growth and transcription factors, with transgenic studies suggesting a role in thymocyte selection, identified in several isoforms. The anti-BCL2L11 antibody can be used for Western blot (1/500-1/2000), Immunocytochemistry (1/50-1/200), Immunohistochemistry-paraffin (1/50-1/200).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79899/1987_A9_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26332/67816_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26332/67816_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26332/67816_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26332/67816_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26332/67816_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26332/67816_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (U-266/70)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000153094-BCL2L11
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Specifications
- Immunogen
- Recombinant human Bim, aa 1-40.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse BCL2L11
- Species Reactivity
- Human, Mouse
- Applications
- WB, ICC, IF, IHC-P, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunocytochemistry (ICC): 1/50-1/200
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Target
- Alternative Names
- BCL2 Like 11; BCL2-Like 11 (Apoptosis Facilitator); BIM; Bcl-2 Interacting Mediator Of Cell Death; Bcl2-Interacting Mediator Of Cell Death; Bcl-2-Related Ovarian Death Agonist;
- Gene ID
- 10018
- UniProt ID
- O43521
- Long Name
- BCL2 Like 11
- Cellular Localization
- Endomembrane system; Mitochondrion
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "BCL2L11"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3251z | Mouse Anti-BCL2L11 Recombinant Antibody (clone 1A12) | WB, ELISA, ICC, IF | Mouse IgG1 |
| MRO-0181-CN | Rabbit Anti-BCL2L11 Recombinant Antibody (clone CBACN-071) | WB, IF, IHC, IP | Rabbit IgG |
| VS3-CJ150 | Rabbit Anti-BCL2L11 Recombinant Antibody (VS3-CJ150) | WB, ICC, IHC, IP | Rabbit IgG |
| VS3-FY154 | Recombinant Rabbit Anti-BCL2L11 Antibody (clone R08-5A2) | WB, IHC-F, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0345 | Hi-Affi™ Rabbit Anti-BCL2L11 Recombinant Antibody (clone DS345AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| MOR-4540 | Hi-Affi™ Rabbit Anti-BCL2L11 Recombinant Antibody (clone TH48DS) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY233 | Anti-BCL2L11 Immunohistochemistry Kit | IHC | |
| VS-0525-XY736 | Anti-Mouse BCL2L11 Immunohistochemistry Kit | IHC | |
| VS-0525-XY735 | Anti-Human BCL2L11 Immunohistochemistry Kit | IHC |
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