Mouse Anti-BST2 Recombinant Antibody (VS3-FY2638)
CAT#: VS3-FY2638
The mouse anti-BST2 recombinant monoclonal antibody has been developed to target CD317 protein, a calculated weight of 19.8 kDa. It cross-reacts with human. This monoclonal antibody is potential for conducting research on Stomatitis and Colorado Tick Fever. This monoclonal antibody can be used in Immunohistochemistry, Immunocytochemistry, Flow cytometry, ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73472/1920_E3_7_cr5cc2b8004d589_selected.jpg
Normal Tissue
Figure 2 Adrenal gland
High expression in adrenal gland
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_B_4_5_val_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_9_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_6_6.jpg
Normal Tissue
Figure 8 Placenta
Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_1_7.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+ RasG12V, Karpas-707)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130303-BST2
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Bone marrow stromal cell antigen 2 of human
- Species Reactivity
- Human
- Applications
- IHC, ICC, FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 19.8 kDa.
- Related Disease
- Stomatitis and Colorado Tick Fever
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Bone Marrow Stromal Cell Antigen 2; HM1.24 Antigen; TETHERIN; BST-2; Bone Marrow Stromal Antigen 2; CD317 Antigen; NPC-A-7; CD317
- Gene ID
- 684
- Sequence Similarities
- Belongs to the tetherin family.
- Cellular Localization
- Golgi apparatus, trans-Golgi network
Cell membrane; Single-pass type II membrane protein
Cell membrane; Lipid-anchor, GPI-anchor
Membrane raft
Cytoplasm
Apical cell membrane
- Post Translation Modifications
- Monoubiquitinated by KSHV E3 ubiquitin-protein ligase K5, leading to its targeting to late endosomes and degradation.
The GPI anchor is essential for its antiviral activity.
Glycosylation at Asn65, Asn92, Thr121, Thr122, and Ser131
Ubiquitination at Lys18
Modification sites at PhosphoSitePlus
Glycosylation from Gly
Glycosylation from GlyGen 6 sites, 9 N-linked glycans (2 sites), 2 O-linked glycans (4 sites)
- Protein Refseq
- NP_004326.1
- Function
- Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other.
The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface.
In either case, their spread as cell-free virions is restricted.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "BST2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1680z | Mouse Anti-BST2 Recombinant Antibody (clone 19H4) | WB, ELISA, IHC | Mouse IgG2b |
| FN-136CQ | Rat Anti-BST2 Recombinant Antibody (clone JF05-1C2.4.1) | Depletion | Rat IgG2b |
| FN-202CQ | Rat Anti-BST2 Recombinant Antibody (clone CBL-1335) | FC, FuncS | Rat IgG2b, κ |
| HPAB-N0026-YC | Mouse Anti-BST2 Recombinant Antibody (clone 1C12C6) | ELISA, WB, IHC | Mouse IgG |
| HPAB-1004-FY | Human Anti-BST2 Recombinant Antibody (clone 4LD) | FC | Chimeric (mouse/human) IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G002E | Anti-BST2 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1295CL | Human Anti-BST2 Recombinant Antibody (TAB-1295CL) | Cyt, FC | Humanized IgG1 |
| TAB-1298CL | Anti-Human BST2 Recombinant Antibody | ELISA | Humanized antibody |
| TAB-1295CL-S(P) | Human Anti-BST2 Recombinant Antibody; scFv Fragment (TAB-1295CL-S(P)) | FC | Humanized scFv |
| TAB-1295CL-F(E) | Human Anti-BST2 Recombinant Antibody; Fab Fragment (TAB-1295CL-F(E)) | FC | Humanized Fab |
| TAB-1298CL-F(E) | Anti-Human BST2 Recombinant Antibody Fab Fragment | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1297CL | Chimeric Anti-Human BST2 Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-1297CL-S(P) | Chimeric Anti-Human BST2 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-1297CL-F(E) | Chimeric Anti-Human BST2 Recombinant Antibody Fab Fragment | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC143 | PE-A*02:01/Human HM1.24 (KLQDASAEV) MHC Tetramer | FCM | |
| MHC-LC144 | APC-A*02:01/Human HM1.24 (KLQDASAEV) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-072CQ | Mouse Anti-BST2 Recombinant Antibody (clone 26F8) | FC, FuncS, Neut | Mouse IgG1, κ |
| NEUT-073CQ | Rat Anti-Bst2 Recombinant Antibody (VMC170) | Neut, FC, IF, IHC, IHC-Fr, IHC-P | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0390 | Hi-Affi™ Rabbit Anti-BST2 Recombinant Antibody (clone DS390AB) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0026-YC-S(P) | Mouse Anti-BST2 Recombinant Antibody (clone 1C12C6); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| HPAB-1004-FY-F(E) | Mouse Anti-BST2 Recombinant Antibody (clone 4LD); scFv Fragment | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0026-YC-F(E) | Mouse Anti-BST2 Recombinant Antibody (clone 1C12C6); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
| HPAB-1004-FY-S(P) | Human Anti-BST2 Recombinant Antibody (clone 4LD); Fab Fragment | FC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC926 | AbPlus™ Anti-BST2 Magnetic Beads (VS-0724-YC926) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC255 | Recombinant Anti-BST2 Vesicular Antibody, EV Displayed (VS-0425-YC255) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY844 | Anti-BST2 Immunohistochemistry Kit | IHC |
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