Rabbit Anti-C1QA Recombinant Antibody (clone R29-1P-7)

CAT#: VS3-XY3282

It is a recombinant rabbit antibody targeting the C1QA (Complement C1q A chain). It recognizes and binds to human C1QA. It also has cross-reactivity against rat BCL11A. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin.

Gene Expression
Figure 1 Duodenum Figure 2 Colon Figure 3 Lymph node Figure 4 RNA cell line category: Cell line enhanced (HMC-1, NB-4, RPMI-8226, SCLC-21H)

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Rat C1QA
  • Species Reactivity
  • Human, Rat
  • Clone
  • R29-1P-7
  • Related Disease
  • C1q deficiency 1 (C1QD1)

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/100-1/200

Target

  • Alternative Names
  • C1QD1
  • Long Name
  • Complement C1q A chain
  • Cellular Localization
  • Secreted
  • Post Translation Modifications
  • O-linked glycans are assumed to be the Glc-Gal disaccharides typically found as secondary modifications of hydroxylated lysines in collagen-like domains.
  • Function
  • C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Recommended Dilution Buffer

Secondary Antibody

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