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  • Rat Anti-C9orf72 Recombinant Antibody (VS-0224-FY23)

Rat Anti-C9orf72 Recombinant Antibody (VS-0224-FY23) (CAT#: VS-0224-FY23)

This is a rat monoclonal antibody that specifically designed for the detection of Guanine nucleotide exchange C9orf72. It is engineered to target an epitope located within 16 amino acids from the N-terminal half. The observed molecular weight of this antibody is approximately 54 kDa, while the calculated weight stands at 54.33 kDa. It recognizes hC9-S and hC9-L as well as mC9-1.


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Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line PC-3
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/1034_E3_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/ihc_selected.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/51671_A_9_3.jpg
Figure 4 Kidney
Figure 4 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/51671_A_7_5.jpg
Figure 5 Testis
Figure 5 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/51671_A_4_6.jpg
Figure 6 Heart muscle
Figure 6 Heart muscle
(Cardiomyocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/51671_B_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23873/51671_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000147894-C9orf72

Specifications

  • Immunogen
  • The 16 amino acids from the N-terminal half of human C9orf72.
  • Host Species
  • Rat
  • Type
  • Rat IgG1, κ
  • Specificity
  • Human and Mouse C9orf72
  • Species Reactivity
  • Human, Mouse
  • Applications
  • Western Blot, Immunohistochemistry, ELISA, Immunofluorescence, Immunocytochemistry
  • Conjugate
  • Unconjugated
  • MW
  • The observed molecular weight of this antibody is approximately 54 kDa, while the calculated weight stands at 54.33 kDa.
  • Related Disease
  • Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1 and Amyotrophic Lateral Sclerosis 1

Product Property

  • Purity
  • >95%
  • Format
  • Liquid
  • Concentration
  • 1 mg/mL
  • Buffer
  • 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl.
  • Preservative
  • 0.05% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western blot: 1/250

Target

  • Alternative Names
  • ALSFTD; DENND9; FTDALS; DENNL72; FTDALS1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "C9orf72"

Recombinant Antibody

CAT Product Name Application Type
HPAB-0359-FY Human Anti-C9orf72 Recombinant Antibody (HPAB-0359-FY) Neut, FC, Block, FuncS, WB Human IgG
HPAB-0360-FY Human Anti-C9orf72 Recombinant Antibody (HPAB-0360-FY) Neut, FC, Block, FuncS, WB Human IgG
VS3-FY176 Recombinant Mouse Anti-C9orf72 Antibody (clone 4D5G1) ELISA, IHC, FC Mouse IgG1
VS3-FY177 Recombinant Mouse Anti-C9orf72 Antibody (clone 6D6F12) ELISA, WB, IHC, ICC, FC Mouse IgG2b

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0359-FY-S(P) Human Anti-C9orf72 Recombinant Antibody; scFv Fragment (HPAB-0359-FY-S(P)) WB, IP, ELISA Human scFv
HPAB-0360-FY-S(P) Human Anti-C9orf72 Recombinant Antibody; scFv Fragment (HPAB-0360-FY-S(P)) WB, IP, ELISA Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0359-FY-F(E) Human Anti-C9orf72 Recombinant Antibody; Fab Fragment (HPAB-0359-FY-F(E)) WB, IP, ELISA Human Fab
HPAB-0360-FY-F(E) Human Anti-C9orf72 Recombinant Antibody; Fab Fragment (HPAB-0360-FY-F(E)) WB, IP, ELISA Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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