Afuco™ Anti-CA9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H43)
CAT#: AFC-TAB-H43
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Chimeric antibody to Human CA9.
Gene Expression
Normal Tissue
Figure 1 Immunofluorescent staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5100/639_D5_2_selected.jpg
Normal Tissue
Figure 2 Stomach
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55207/139851_A_5_1.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (A-431, HDLM-2, hTERT-RPE1, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107159-CA9
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Specifications
- Host Species
- Chimeric
- Derivation
- Chimeric
- Type
- ADCC enhanced antibody
- Specificity
- CA9 (carbonic anhydrase IX, CAIX, MN, G250) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Trade name
- Redectane
- Generic Name
- Girentuximab
- Related Disease
- Kidney tumours
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Girentuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Girentuximab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Girentuximab"
Anti-CAIX/CA9 Recombinant Antibody (Girentuximab)Recombinant chimeric antibody expressed in CHO binding to human CAIX. Girentuximab is a chimeric monoclonal antibody designed for the treatment of renal cell carcinoma.
DrugMonitor™ Anti-Girentuximab Antibody (VS-1224-YC521)Girentuximab is a chimeric (mouse/human) monoclonal antibody targeting carbonic anhydrase IX, expressed in 95% of clear cell renal cell carcinomas (RCC). The DrugMonitor™ Anti-Girentuximab Antibody (VS-1224-YC521) is an anti-drug antibody (ADA) against Girentuximab. This drug-based antibody is raised in mice immunized with the Girentuximab. The anti-Girentuximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Girentuximab in samples.
See other products for "CA9"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-707 | Anti-CAIX/CA9 Recombinant Antibody (Girentuximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-H43 | Anti-Human CA9 Recombinant Antibody (TAB-H43) | ELISA, IP, IF, Inhib | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1454CL-S(P) | Anti-Human CA9 Recombinant Antibody scFv Fragment (G250) | Cyt | |
| TAB-1455CL-S(P) | Anti-Human CA9 Recombinant Antibody scFv Fragment (S239D/I332E) | SPR | |
| TAB-1456CL-S(P) | Anti-Human CA9 Recombinant Antibody scFv Fragment (MSC1) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1457CL-S(P) | Anti-Human CA9 Recombinant Antibody scFv Fragment (MSC2) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1459CL-S(P) | Anti-Human CA9 Recombinant Antibody scFv Fragment (MSC4) | ELISA, FC, Inhib | Fully human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1458CL-S(P) | Anti-Human CA9 Recombinant Antibody (MSC3); scFv Fragment | FC | Human scFv |
| HPAB-0355-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0355-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0356-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0356-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0357-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0357-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0358-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0358-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1458CL-F(E) | Anti-Human CA9 Recombinant Antibody (MSC3); Fab Fragment | FC | Human Fab |
| HPAB-0355-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0355-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| HPAB-0356-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0356-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| HPAB-0357-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0357-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| HPAB-0358-CN-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0358-CN-F(E)) | WB, ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0427 | Hi-Affi™ Rabbit Anti-CA9 Recombinant Antibody (clone DS427AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0782-CN | Human Anti-CA9 Recombinant Antibody (clone G119) | FC, ELISA, Inhib, Cyt, Bioimaging | Human IgG |
| HPAB-0784-CN | Human Anti-CA9 Recombinant Antibody (clone G37) | FC, ELISA, Inhib, FuncS, Cyt, Bioimaging, IHC | Human IgG |
| VS3-QX140 | Mouse Anti-CA9 Recombinant Antibody (clone 5B5-B10-A2) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS7-HM283 | Mouse Anti-CA9 Recombinant Antibody (clone 2D3) | WB, IHC, FCM | Mouse IgG1 |
| VS7-HM284 | Mouse Anti-CA9 Recombinant Antibody (clone CBL090HM) | WB, IHC-p, IF, FCM, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY37 | AbPlus™ Anti-CA9 Magnetic Beads (12F10) | IP, Protein Purification | |
| VS-0724-YC1029 | AbPlus™ Anti-CA9 Magnetic Beads (VS-0724-YC1029) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY54 | Human Anti-CA9 (clone G37) scFv-Fc Chimera | FC, ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY290 | Anti-CA9 Immunohistochemistry Kit | IHC | |
| VS-0525-XY911 | Anti-Mouse CA9 Immunohistochemistry Kit | IHC | |
| VS-0525-XY912 | Anti-Human CA9 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC94 | Recombinant Anti-CA9 Vesicular Antibody, EV Displayed (VS-0425-YC94) | ELISA, FC, Neut, Cell-uptake |
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