Mouse Anti-CBR1 Recombinant Antibody (VS3-FY2649) (CAT#: VS3-FY2649)
The anti-CBR1 antibody has been genetically engineered to specifically target human CBR1 protein. It exhibits cross-reactivity with mouse and rat. This monoclonal antibody proves valuable in disease research related to Down Syndrome and Depersonalization Disorder.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18433/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18433/if_selected.jpg
Figure 2 Duodenum
(High expression in duodenum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18433/42081_A_7_2_val_selected.jpg
(High expression in duodenum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18433/42081_A_7_2_val_selected.jpg
Figure 3 Small intestine.
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_6_2_val_selected.jpg
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_6_2_val_selected.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_5_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_5_6.jpg
Figure 5 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_7_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_7_3.jpg
Figure 6 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_9_4.jpg
Figure 7 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_7_5.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159228-CBR1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159228-CBR1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Carbonyl reductase 1 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC
- Conjugate
- Unconjugated, FITC
- Related Disease
- Down Syndrome and Depersonalization Disorder
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunocytochemistry: 1/50-1/200
Target
- Alternative Names
- Carbonyl Reductase 1; Short Chain Dehydrogenase/Reductase Family 21C Member 1; NADPH-Dependent Carbonyl Reductase 1; Prostaglandin-E(2) 9-Reductase; Prostaglandin 9-Ketoreductase; EC 1.1.1.184; SDR21C1; CBR; Short Chain Dehydrogenase/Reductase Family 21C, Member 1
- Gene ID
- 873
- UniProt ID
- P16152
- Sequence Similarities
- Belongs to the short-chain dehydrogenases/reductases (SDR) family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Ubiquitination at Lys174 and Lys186
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001273718.1; NP_001748.1
- Function
- Can convert prostaglandin E to prostaglandin F2-alpha (By similarity).
Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.
Catalyzes the reduction of S-nitrosoglutathione.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CBR1"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0347CT | Mouse Anti-CBR1 Recombinant Antibody (clone 5F23) | ELISA, WB | Mouse IgG2a |
| ZG-0367F | Mouse Anti-CBR1 Recombinant Antibody (ZG-0367F) | WB, ICC | Mouse IgG |
| VS3-XY169 | Mouse Anti-CBR1 Recombinant Antibody (clone 2C9-B12-C4) | WB, ICC | Mouse IgG1 |
| VS4-WK65 | Mouse Anti-CBR1 Recombinant Antibody (VS4-WK65) | ELISA, WB, ICC | Mouse IgG1 |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-FY2649. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
-1.png)
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, FC, WB, Block
Application: ELISA
Application: ELISA, IF, Block, FuncS
Application: ELISA, FC, Inhib, IHC-Fr, WB, IP
Application: ELISA, Neut
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
