Mouse Anti-CBR1 Recombinant Antibody (VS3-FY2649)
CAT#: VS3-FY2649
The anti-CBR1 antibody has been genetically engineered to specifically target human CBR1 protein. It exhibits cross-reactivity with mouse and rat. This monoclonal antibody proves valuable in disease research related to Down Syndrome and Depersonalization Disorder.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18433/if_selected.jpg
Normal Tissue
Figure 2 Duodenum
High expression in duodenum
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18433/42081_A_7_2_val_selected.jpg
Normal Tissue
Figure 3 Small intestine.
High expression in small intestine
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_6_2_val_selected.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_5_6.jpg
Normal Tissue
Figure 5 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_7_3.jpg
Normal Tissue
Figure 6 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_9_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34291/168609_A_7_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000159228-CBR1
❮
❯
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Carbonyl reductase 1 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC
- Conjugate
- Unconjugated, FITC
- Related Disease
- Down Syndrome and Depersonalization Disorder
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunocytochemistry: 1/50-1/200
Target
- Alternative Names
- Carbonyl Reductase 1; Short Chain Dehydrogenase/Reductase Family 21C Member 1; NADPH-Dependent Carbonyl Reductase 1; Prostaglandin-E(2) 9-Reductase; Prostaglandin 9-Ketoreductase; EC 1.1.1.184; SDR21C1; CBR; Short Chain Dehydrogenase/Reductase Family 21C, Member 1
- Gene ID
- 873
- UniProt ID
- P16152
- Sequence Similarities
- Belongs to the short-chain dehydrogenases/reductases (SDR) family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Ubiquitination at Lys174 and Lys186
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001273718.1; NP_001748.1
- Function
- Can convert prostaglandin E to prostaglandin F2-alpha (By similarity).
Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.
Catalyzes the reduction of S-nitrosoglutathione.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-FY2649. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "CBR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0347CT | Mouse Anti-CBR1 Recombinant Antibody (clone 5F23) | ELISA, WB | Mouse IgG2a |
| ZG-0367F | Mouse Anti-CBR1 Recombinant Antibody (ZG-0367F) | WB, ICC | Mouse IgG |
| VS3-XY169 | Mouse Anti-CBR1 Recombinant Antibody (clone 2C9-B12-C4) | WB, ICC | Mouse IgG1 |
| VS4-WK65 | Mouse Anti-CBR1 Recombinant Antibody (VS4-WK65) | ELISA, WB, ICC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0491 | Hi-Affi™ Rabbit Anti-CBR1 Recombinant Antibody (clone DS491AB) | WB, IHC-P, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC281 | AbPlus™ Anti-CBR1 Magnetic Beads (VS-0724-YC281) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1034 | Anti-CBR1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, Cyt, Stim, PP, Agonist
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC
Application: Inhib, FC, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
