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    Human Anti-CBX1 Recombinant Antibody (clone RAB-C145) (CAT#: VS11-QX15)

    This product is a recombinant human antibody that recognizes CBX1. This antibody can be used for the following applications: ELISA, IF, IP-MS, ChIP.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/610_F6_2_selected.jpg
    Figure 2 IHC staining of human cerebellum
    Figure 2 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong nuclear positivity in cerebellar tissue.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/ihc_selected.jpg
    Figure 3 IF staining of human cell line A-431
    Figure 3 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/617_F6_1_red_green.jpg
    Figure 4 IF staining of human cell line U-2 OS
    Figure 4 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/613_F6_1_red_green.jpg
    Normal Tissue
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Glial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Neuronal cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/27516_B_8_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Glandular cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Peripheral nerve/ganglion
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/27516_A_9_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Cholangiocytes
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/27516_A_7_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in glomeruli
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/27516_A_7_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Pachytene spermatocytes
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Peritubular cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Preleptotene spermatocytes
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Round or early spermatids
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Spermatogonia cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/27516_A_6_6.jpg
    Figure 10 Lymph node
    Figure 10 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12265/27516_A_9_8.jpg
    RNA Expression
    Figure 11 RNA cell line category: Low cell line specificity
    Figure 11 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000108468-CBX1

    Specifications

    • Immunogen
    • CBX1 protein
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • Human IgG1, κ
    • Specificity
    • Human CBX1
    • Species Reactivity
    • Human
    • Clone
    • RAB-C145
    • Applications
    • ELISA, IF, IP-MS, ChIP
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • 1 mg/mL (Please refer to the vial label for the specific concentration.)
    • Buffer
    • 0.2 μm filtered solution in PBS
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipped at 4°C.

    Target

    • Alternative Names
    • Chromobox Homolog 1; Heterochromatin Protein 1 Homolog Beta; Modifier 1 Protein; HP1Hsbeta; P25beta; CBX; M31; Chromobox Homolog 1 (HP1 Beta Homolog Drosophila); Chromobox Homolog 1 (Drosophila HP1 Beta); Heterochromatin Protein P25 Beta; HP1 Beta Homolog (Drosophila); Heterochromatin Protein 1-Beta; Heterochromatin Protein P25; HP1 Beta Homolog; HP1Hs-Beta; HP1-BETA; HP1 Beta; MOD1
    • Long Name
    • Chromobox protein homolog 1
    • Cellular Localization
    • Nucleoplasm, Nuclear bodies
    • Function
    • Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.

    Recommended Products

    Isotype Control

    Recommended Dilution Buffer

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CBX1"

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    CAT Product Name Application Type
    DrMAB-268 Human Anti-CBX1 Recombinant Antibody (clone D256); Fab Fragment IF, ELISA, IP-MS, ChIP Human Fab

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