AibGenesis™ Rabbit Anti-CBX5 Recombinant Antibody (AibG-Rb-CB291)
CAT#: VS-0426-FY291
Discovered using our AI-powered antibody discovery platform, this Protein A purified Rabbit IgG targets CBX5 (HP1 alpha). Validated for WB, IHC, and ELISA, it offers researchers high specificity for monitoring constitutive heterochromatin maintenance and DNA damage response signaling.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16699/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16699/164_F10_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17548/971_A3_1_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17548/39008_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17548/39008_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17548/39008_A_8_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000094916-CBX5
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Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG, Kappa
- Specificity
- Human CBX5
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-CB291
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, ELISA, Immunoprecipitation
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Metastatic Breast Cancer
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- PBS, 0.05% Protective protein, 50% Glycerol
- Preservative
- 0.05% Proclin 300
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:1000-1:5000), Immunohistochemistry (1:400-1:2000), Immunocytochemistry/Immunofluorescence (1:200-1:1000), ELISA (1:5000-1:20000), Immunoprecipitation (1:50-1:200)
Target
- Alternative Names
- Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
- Gene ID
- 23468
- UniProt ID
- P45973
- Long Name
- Chromobox 5
- Cellular Localization
- Centromere, Chromosome, Nucleus
- Function
- HP1 alpha; binds methylated histone H3K9 to promote heterochromatin formation and gene silencing.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CBX5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-276 | Human Anti-CBX5 Recombinant Antibody (clone D244); Fab Fragment | ELISA, IP-MS, ChIP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-277 | Human Anti-CBX5 Recombinant Antibody (clone D399) | ELISA, IP-MS | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2404MZ | Mouse Anti-CBX5 Recombinant Antibody (clone nBcdbn 25309) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0498 | Hi-Affi™ Rabbit Anti-CBX5 Recombinant Antibody (clone DS498AB) | WB, IP, IHC-P, FC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0764-CN | Mouse Anti-CBX5 Recombinant Antibody (clone B0-1) | WB, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0765-CN | Rabbit Anti-CBX5 Recombinant Antibody (clone CBACN-283) | WB, IF, IHC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0036F | Mouse Anti-CBX5 Recombinant Antibody (clone 2G2) | WB, IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY43 | AbPlus™ Anti-CBX5 Magnetic Beads (D399) | IP-MS, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY326 | Anti-CBX5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1041 | Anti-Mouse CBX5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1040 | Anti-Human CBX5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1042 | Anti-Rat CBX5 Immunohistochemistry Kit | IHC |
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