Human Anti-CCR4 Recombinant Antibody (clone 17G) (CAT#: HPAB-1004WJ)
This product is a human antibody binds to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4.
Specific Inquiry
FC
Figure 1. Different concentrations of 17G, 9E and KM3060var antibodies were tested in flow cytometry for binding to avian DT40 cells stably transfected with human CCR4.
Hagemann, U. B., Gunnarsson, L., Geraudie, S., Scheffler, U., Griep, R. A., Reiersen, H., ... & Kiprijanov, S. M. (2014). Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis. PLoS One, 9(7).
Specifications
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- Human CCR4
- Species Reactivity
- Human
- Clone
- 17G
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The 17G antibody has been reported in applications of FC.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- C-C Motif Chemokine Receptor 4; Chemokine (C-C Motif) Receptor 4; C-C CKR-4; CC-CKR-4; CMKBR4; CCR-4; K5-5; C-C Chemokine Receptor Type 4;
- Gene ID
- 1233
- UniProt ID
- P51679
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 17G"
See other products for "CCR4"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-187 | Human Anti-CCR4 Recombinant Antibody (TAB-187) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG1, κ |
| TAB-1530CL | Human Anti-CCR4 Recombinant Antibody (TAB-1530CL) | Depletion, FuncS | Human IgG4 |
| TAB-1530CL-S(P) | Human Anti-CCR4 Recombinant Antibody; scFv Fragment (TAB-1530CL-S(P)) | Depletion, FuncS | Human scFv |
| TAB-1530CL-F(E) | Human Anti-CCR4 Recombinant Antibody; Fab Fragment (TAB-1530CL-F(E)) | Depletion, FuncS | Humanized Fab |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G005D | Anti-CCR4 immunotoxin (scFv)-DT | Cytotoxicity assay, Function study |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-100CL | Human Anti-CCR4 Recombinant Antibody (TAB-100CL) | ELISA | Human IgG |
| TAB-1521CL-F(E) | Anti-Human CCR4 Recombinant Antibody Fab Fragment (208) | FC, Inhib | Human antibody |
| TAB-1522CL-F(E) | Anti-Human CCR4 Recombinant Antibody Fab Fragment (306) | FC, Inhib | Human antibody |
| TAB-1523CL-F(E) | Anti-Human CCR4 Recombinant Antibody Fab Fragment (308) | FC, Inhib | Human antibody |
| TAB-1524CL-F(E) | Anti-Human CCR4 Recombinant Antibody Fab Fragment (406) | FC, Inhib | Human antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABZ-142 | Human Anti-CCR4 Recombinant Antibody (clone KM3060) | WB | Chimeric (mouse/human) IgG1, κ |
| HPAB-1777LY | Mouse Anti-CCR4 Recombinant Antibody (HPAB-1777LY) | FC, Inhib, ELISA | Mouse IgG |
| HPAB-1778LY | Mouse Anti-CCR4 Recombinant Antibody (HPAB-1778LY) | FC, Inhib, ELISA | Mouse IgG |
| HPAB-1779LY | Mouse Anti-CCR4 Recombinant Antibody (HPAB-1779LY) | FC, Inhib, ELISA | Mouse IgG |
| HPAB-1780LY | Human Anti-CCR4 Recombinant Antibody (HPAB-1780LY) | FC, Inhib, ELISA | Humanized IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0047-FY-F(E) | Human Anti-CCR4 Recombinant Antibody; Fab Fragment (HPAB-0047-FY-F(E)) | FC | Human Fab |
| HPAB-1109WJ-F(E) | Human Anti-CCR4 Recombinant Antibody; Fab Fragment (HPAB-1109WJ-F(E)) | FC | Humanized Fab |
| HPAB-1268WJ-F(E) | Mouse Anti-CCR4 Recombinant Antibody; Fab Fragment (HPAB-1268WJ-F(E)) | ELISA, WB, FC | Mouse Fab |
| MOB-213YJL-F(E) | Chimeric (Mouse/Human) Anti-CCR4 Recombinant Antibody (clone chKM2760); Fab Fragment | ELISA, FC, FuncS | Chimeric (mouse/human) Fab |
| HPAB-1370WJ-F(E) | Human Anti-CCR4 Recombinant Antibody; Fab Fragment (clone KM2760) | ELISA, WB | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-187 | Afuco™ Anti-CCR4 Recombinant Antibody (AFC-TAB-187), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | Human IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1004WJ-S(P) | Human Anti-CCR4 Recombinant Antibody (clone 17G); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-1005WJ-S(P) | Human Anti-CCR4 Recombinant Antibody (clone 9E); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-1006WJ-S(P) | Human Anti-CCR4 Recombinant Antibody (clone 1O); scFv Fragment | ELISA, WB | Human scFv |
| MOB-213YJL-S(P) | Mouse Anti-CCR4 Recombinant Antibody (clone chKM2760); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
| HPAB-1370WJ-S(P) | Human Anti-CCR4 Recombinant Antibody; scFv Fragment (clone KM2760) | ELISA, WB | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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