Rabbit Anti-CCR7 Polyclonal Antibody (VS13-YC151) (CAT#: VS13-YC151)
The Rabbit Anti-CCR7 Polyclonal Antibody is specific for human, mouse and rat CCR7. CCR7, involved in chemokine receptor signaling, affects diseases like dermatitis through pathways that manage cell migration and immune sensing, with critical ligand interactions. The anti-CCR7 antibody can be used for Western blot (1/500-1/2000), ELISA (1/5000-1/10000), Immunohistochemistry-paraffin (1/100-1/500), Immunocytochemistry (1/100), Immunofluorescence (1/100-1/500).
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31383/1522_F9_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31383/1522_F9_3_selected.jpg
Figure 2 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74467/1566_C10_2_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74467/1566_C10_2_selected.jpg
Figure 3 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_3.jpg
Figure 4 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_8.jpg
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3796/10959_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126353-CCR7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126353-CCR7
Specifications
- Immunogen
- Recombinant human CCR7 (aa 25-59) conjugated with KLH.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat CCR7
- Species Reactivity
- Human, Mouse, Rat, Dog (Predicted)
- Applications
- WB, ELISA, IHC-P, ICC, IF
- Conjugate
- NONE
- Related Disease
- Chronic Actinic Dermatitis and Pars Planitis
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01× TBS (pH 7.4) containing 50% Glycerol and 1% BSA.
- Preservative
- 0.03% Proclin 300
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
ELISA: 1/5000-1/10000
Immunohistochemistry-paraffin (IHC-P): 1/100-1/500
Immunocytochemistry (ICC): 1/100
Immunofluorescence (IF): 1/100-1/500
Target
- Alternative Names
- C-C Motif Chemokine Receptor 7; Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1; Chemokine (C-C Motif) Receptor 7; MIP-3 Beta Receptor; CC-CKR-7; CMKBR7; CDw197; CCR-7; EBI1; BLR2; Lymphocyte-Specific G Protein-Coupled Peptide Receptor;
- Gene ID
- 1236
- UniProt ID
- P47774
- Long Name
- C-C Motif Chemokine Receptor 7
- Cellular Localization
- Cell membrane
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-161-F(E) | Recombinant Anti-human CCR7 Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| MHH-161-F(E) | Recombinant Human Anti-human CCR7 Antibody Fab Fragment | WB, IP, FuncS | Fab |
| HPAB-0473-CN-F(E) | Mouse Anti-CCR7 Recombinant Antibody; Fab Fragment (HPAB-0473-CN-F(E)) | ELISA, FC, Block | Mouse Fab |
| HPAB-0474-CN-F(E) | Human Anti-CCR7 Recombinant Antibody; Fab Fragment (HPAB-0474-CN-F(E)) | ELISA, FC, Block | Humanized Fab |
| HPAB-0362-YC-F(E) | Human Anti-CCR7 Recombinant Antibody; Fab Fragment (HPAB-0362-YC-F(E)) | FC, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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