Anti-CD1C (clone W24V7) Recombinant Antibody Coupled Liposome (VS-1024-FY8)
CAT#: VS-1024-FY8
Anti-BDCA-1 antibody-conjugated liposomes are a novel drug delivery system specifically targeting immune cells marked by BDCA-1. These liposomes can precisely deliver drugs to target cells through specific binding to BDCA-1, enhancing the therapeutic efficacy of the drugs. Due to their targeting capability, anti-BDCA-1 antibody-conjugated liposomes have shown promising application potential in cancer treatment and autoimmune disease research. This technology is expected to offer safer and more effective treatment options in the future of precision medicine.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line JURKAT
Immunofluorescent staining of human cell line JURKAT shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68359/1970_G5_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000158481-CD1C
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More Infomation
Specifications
- Potential Clinical Applications
- Specific targeting of dendritic cells
Product Composition
- Clone
- W24V7
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This product is a recombinant antibody derived from mice, specifically designed to target the BDCA-1 molecule. BDCA-1, also known as blood dendritic cell antigen-1, is a key surface marker commonly found on a subset of dendritic cells. These immune cells play a vital role in the body's immune response by capturing and presenting antigens to T cells, thereby initiating and regulating immune reactions.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- CD1C
- Introduction
- CD1C (CD1c Molecule) is a Protein Coding gene. Diseases associated with CD1C include Mycobacterium Malmoense and Foramen Magnum Meningioma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include beta-2-microglobulin binding and lipopeptide binding. An important paralog of this gene is CD1B.
- Alternative Names
- CD1c Molecule; CD1C Antigen, C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; T-Cell Surface Glycoprotein CD1c; Cortical Thymocyte Antigen CD1C
- Full Name
- CD1c Molecule
- Gene ID
- 911
- UniProt ID
- P29017
- Cellular Localization
- Cell membrane; Single-pass type I membrane protein; Endosome membrane; Single-pass type I membrane protein; Lysosome
- Post Translation Modifications
- Glycosylation at Asn38, Asn70, Asn75, and Asn146 ( NX_P29017 [NX_P29017-1] )
Ubiquitination at Lys197 ( NX_P29017 [NX_P29017-1] )
Modification sites at PhosphoSitePlus ( P29017 )
Glycosylation from GlyGen (P29017) 5 sites
- Protein Refseq
- XP_005245636.1; XP_054195514.1; NP_001756.2
- Function
- Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
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Datasheet
MSDS
COA
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