Human Anti-CD274 Recombinant Antibody (clone hAb7) (CAT#: HPAB-1907LY)
This product is an antibody that recognizes CD274. The antibody hAb7 can be used for immunoassay techniques such as: ELISA, FC.
Specific Inquiry
FC
Figure 1 The binding of humanized PD-L1 antibodies to PD-L1 expressing CHO cell as measured by FACS analysis.
FC
Figure 2 The binding of humanized PD-L1 antibodies to PD-L1 expressed on activated dendritic cells (DC) as measured by FACS analysis.
EC50 is provided in nM.
Figure 3 The PD-L1 antibodies bind to cynomolgus monkey PD-L1.
EC50 is provided in nM.
Figure 4 The effect of humanized anti-PD-L1 antibodies on IL-2 production in mixed lymphocyte reaction (MLR).
FuncS
Figure 5 Anti-PD-L1 antibodies reverse Treg's suppressive function.
Figure 6 The anti-PD-L1 antibodies lacks ADCC on mDCs.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human CD274
- Species Reactivity
- Human
- Clone
- hAb7
- Applications
- ELISA, FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry and Functional Assay.
Target
- Alternative Names
- CD274 Molecule; CD274 Antigen; B7 Homolog 1; Programmed Cell Death 1 Ligand 1; PDCD1 Ligand 1; PDCD1LG1; PDCD1L1;
- Gene ID
- 29126
- UniProt ID
- Q9NZQ7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone hAb7"
See other products for "Cd274"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-305-sdAb | Recombinant Anti-Mouse Cd274 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| NBD-0065-YJ-VHH | Camelid Anti-CD274 Recombinant Single Domain Antibody (CBP112D) | ELISA | Camelid VHH |
| NBD-0066-YJ-VHH | Camelid Anti-CD274 Recombinant Single Domain Antibody (KN035) | ELISA, Inihb | Camelid VHH |
| NBD-0067-YJ-VHH | Camelid Anti-CD274 Recombinant Single Domain Antibody (Nb1) | ELISA, FC | Camelid VHH |
| NBD-0068-YJ-VHH | Camelid Anti-CD274 Recombinant Single Domain Antibody (Nb2) | ELISA, FC | Camelid VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0190CL | Anti-Human CD274 Recombinant Antibody (PD1-AB1) | FC, ELISA, FuncS | |
| TAB-0997CL | Anti-Human CD274 Recombinant Antibody (B60-55) | ELISA, FuncS, FC, PK | Human antibody |
| TAB-1002CL | Mouse Anti-CD274 Recombinant Antibody (TAB-1002CL) | ELISA, FC | Mouse IgG, κ |
| TAB-1003CL | Human Anti-CD274 Recombinant Antibody (TAB-1003CL) | FC, ELISA | Human IgG |
| TAB-0190CL-S(P) | Anti-Human CD274 Recombinant Antibody scFv Fragment (PD1-AB1) | FC, ELISA, FuncS |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0262CL | Mouse Anti-CD274 Recombinant Antibody (TAB-0262CL) | ELISA, WB, SPR, ADCC, CDC, FuncS | Mouse IgG |
| TAB-0992CL-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0992CL-S(P)) | FC | Mouse scFv |
| TAB-0993CL-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0993CL-S(P)) | FC | Mouse scFv |
| TAB-0994CL-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0994CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-1009CL-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-1009CL-S(P)) | WB, IHC | Mouse scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0995CL | Human Anti-CD274 Recombinant Antibody (TAB-0995CL) | ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
| TAB-0995CL-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0995CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0995CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0995CL-F(E)) | ELISA, FC | Chimeric (Mouse/Human) Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0265CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0265CL-F(E)) | ELISA, WB, SPR, FuncS | Humanized Fab |
| TAB-0266CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0266CL-F(E)) | ELISA, WB, SPR, FuncS | Humanized Fab |
| TAB-0267CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0267CL-F(E)) | ELISA, WB, SPR, FuncS | Humanized Fab |
| TAB-0268CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0268CL-F(E)) | ELISA, WB, SPR, FuncS | Humanized Fab |
| TAB-0996CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0996CL-F(E)) | ELISA, FC | Humanized Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-324CQ | Mouse Anti-CD274 Recombinant Antibody (clone 29E.2A3.C6) | IHC-P, FC, Neut, ICC | Mouse IgG2b, κ |
| NEUT-325CQ | Human Anti-CD274 Recombinant Antibody (clone CBLS-206) | Neut | Human IgG1, κ |
| NEUT-326CQ | Human Anti-CD274 Recombinant Antibody (clone CBLS-207) | ELISA, Neut | Human IgG1, κ |
| NEUT-327CQ | Mouse Anti-CD274 Recombinant Antibody (clone MIH1) | FC, FuncS, Neut, IHC, IF | Mouse IgG1, κ |
| NEUT-330CQ | Rat Anti-CD274 Recombinant Antibody (clone MIH5) | FC, FuncS, Neut, IHC-Fr, WB | Rat IgG2a, λ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-328CQ | Rat Anti-CD274 Recombinant Antibody (VMC171) | Block, FC | Rat IgG2 |
| NEUT-329CQ | Rat Anti-CD274 Recombinant Antibody (clone 10F.9G2) | FC, IF, Block | Rat IgG2b, κ |
| NEUT-331CQ | Mouse Anti-CD274 Recombinant Antibody (clone alphaPD-L1) | ELISA, Block | Mouse IgG1, λ |
| NEUT-332CQ | Rabbit Anti-CD274 Recombinant Antibody (clone CBL1009) | Block | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0548 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone DS548AB) | ELISA | Rabbit IgG |
| MOR-4049 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone SI116DS) | ELISA | Rabbit IgG |
| MOR-4050 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone SI117DS) | ICC, IF, FC | Rabbit IgG |
| MOR-4051 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone SI118DS) | FC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0193-YC-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0193-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-0561LY-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0561LY-F(E)) | ELISA, Block | Chimeric (mouse/human) Fab |
| HPAB-0562LY-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0562LY-F(E)) | ELISA, Block | Chimeric (mouse/human) Fab |
| HPAB-0563LY-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0563LY-F(E)) | ELISA, Block | Chimeric (mouse/human) Fab |
| HPAB-0564LY-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0564LY-F(E)) | ELISA, Block | Chimeric (mouse/human) Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0455-YC | Mouse Anti-CD274 Recombinant Antibody (HPAB-M0455-YC) | ELISA | Mouse IgG |
| HPAB-M0456-YC | Human Anti-CD274 Recombinant Antibody (HPAB-M0456-YC) | ELISA, FC | Humanized IgG |
| HPAB-M0457-YC | Human Anti-CD274 Recombinant Antibody (HPAB-M0457-YC) | ELISA, FC, Block, FuncS | Humanized IgG1 |
| HPAB-M0458-YC | Human Anti-CD274 Recombinant Antibody (HPAB-M0458-YC) | ELISA, FC | Humanized IgG |
| HPAB-M0459-YC | Human Anti-CD274 Recombinant Antibody (HPAB-M0459-YC) | ELISA, FC | Humanized IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-417CQ | Afuco™ Anti-CD274 ADCC Recombinant Antibody (Durvalumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| AFC-TAB-418CQ | Afuco™ Anti-CD274 ADCC Recombinant Antibody (Atezolizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0261-YJ-S(P) | Human Anti-CD274 Recombinant Antibody (clone 4736); scFv Fragment | Block, FuncS, ELISA | Human scFv |
| HPAB-0646-WJ-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (HPAB-0646-WJ-S(P)) | ELISA, Block | Human scFv |
| HPAB-3121LY-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (HPAB-3121LY-S(P)) | ELISA | Mouse scFv |
| HPAB-3122LY-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (HPAB-3122LY-S(P)) | ELISA | Mouse scFv |
| HPAB-0482-YJ-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (HPAB-0482-YJ-S(P)) | IHC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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