This product is a mouse-derived IgG monoclonal antibody expressed by hybridoma cells, specifically targeting the human B7-H3 protein. The anti-B7-H3 antibody recognizes cancer stem cell lines, regulates angiogenic factor secretion, and exhibits potent antitumor activity in vivo. HPAB-0048LY significantly reduced VEGF secretion by up to 60% in the subset of cancer stem cell lines examined. HPAB-0048LY-F(E) antibody is the Fab fragment antibody form of HPAB-0048LY antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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