Mouse Anti-CD3 Recombinant Antibody (clone M291) (CAT#: HPAB-0545-WJ)

M291 is a humanized antibody specific for CD3, and therefore M291 is an antibody specific for the human CD3 complex. The M291 antibody may be used for diagnostic purposes in patient immune monitoring and for research purposes in leukocyte subtype classification.


Specific Inquiry
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ELISA

Figure 1 Displacement assay to compare the relative affinity of HuM291-Fos and M291 for their antigen.

Figure 1 Displacement assay to compare the relative affinity of HuM291-Fos and M291 for their antigen.

Cyt

Figure 2 Bispecific antibody induced T cell mediated lysis of 1D10 positive cells.

Figure 2 Bispecific antibody induced T cell mediated lysis of 1D10 positive cells.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human CD3
  • Species Reactivity
  • Human
  • Clone
  • M291
  • Applications
  • ELISA, Cyt, Inhib
  • Related Disease
  • Cancers

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Cytotoxicity, Inhibition.

Target

  • Alternative Names
  • CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone M291"

See other products for "CD3"

Chimeric Antibody

CAT Product Name Application Type
TAB-0417CL Chimeric Anti-Human CD3 Recombinant Antibody ELISA, FC, FuncS Chimeric (mouse/human)
TAB-071LC Anti-Human CD3 Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-072LC Chimeric Anti-Human CD3 Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-071LC-F(E) Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)
TAB-072LC-F(E) Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)

Blocking Antibody

CAT Product Name Application Type
NEUT-339CQ Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) FC, Block, IHC-Fr, IF, WB Mouse IgG2a
NEUT-340CQ Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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