Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-M0466-YC-S(P)) (CAT#: HPAB-M0466-YC-S(P))
HPAB-M0466-YC exhibited similar binding affinity to human CD3 as murine anti-CD3 on human T cells (Jurkat). Additionally, HPAB-M0466-YC displayed strong binding to cynomolgus T cells (HSC-F). The binding of HPAB-M0466-YC to Jurkat cells (which express human CD3+) resulted in an IC50 value of 5.9 nM, while its binding to HSC-F cells (also expressing human CD3+) yielded an IC50 value of 3.8 nM. HPAB-M0466-YC-S(P) antibody is the scfv fragment antibody form of HPAB-M0466-YC antibody. Single-chain variable fragments (scFvs) are artificial constructs consisting of the variable regions of the immunoglobulin heavy and light chains connected by a peptide linker.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human scFv
- Specificity
- Human CD3
- Species Reactivity
- Human, Cynomolgus
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cluster of differentiation 3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "CD3"
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0365CL-S(P) | Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) | IP, IB, FuncS | |
| TAB-0416CL-F(E) | Mouse Anti-CD3 Recombinant Antibody Fab Fragment (TAB-0416CL-F(E)) | IB, ELISA, FC, FuncS | |
| TAB-0422CL-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-0422CL-F(E)) | ELISA | Mouse Fab |
| TAB-070LC-S(P) | Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-070LC-S(P)) | ELISA | Mouse scFv |
| TAB-073LC-S(P) | Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-073LC-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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