Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-M0466-YC-S(P)) (CAT#: HPAB-M0466-YC-S(P))
HPAB-M0466-YC exhibited similar binding affinity to human CD3 as murine anti-CD3 on human T cells (Jurkat). Additionally, HPAB-M0466-YC displayed strong binding to cynomolgus T cells (HSC-F). The binding of HPAB-M0466-YC to Jurkat cells (which express human CD3+) resulted in an IC50 value of 5.9 nM, while its binding to HSC-F cells (also expressing human CD3+) yielded an IC50 value of 3.8 nM. HPAB-M0466-YC-S(P) antibody is the scfv fragment antibody form of HPAB-M0466-YC antibody. Single-chain variable fragments (scFvs) are artificial constructs consisting of the variable regions of the immunoglobulin heavy and light chains connected by a peptide linker.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human scFv
- Specificity
- Human CD3
- Species Reactivity
- Human, Cynomolgus
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cluster of differentiation 3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibodies
Mouse Antibodies
Chimeric Antibodies
Blocking Antibodies
ScFv Antibodies
IgG Antibodies
Fab Antibodies
Single Domain Antibodies
Agonistic Antibodies
NHP Antibodies
ScFv-Fc Chimeras
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0418CL | Humanized Anti-Human CD3 Recombinant Antibody | ELISA, FC, FuncS | Humanized Antibody |
| TAB-075LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-075LC-S(P)) | ELISA | Human scFv |
| TAB-076LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-076LC-S(P)) | ELISA | Human scFv |
| TAB-077LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-077LC-S(P)) | ELISA | Human scFv |
| TAB-078LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-078LC-S(P)) | ELISA | Human scFv |
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