Human Anti-CD3 Recombinant Antibody (clone HuM291) (CAT#: HPAB-0546-WJ)
HuM291-Fos inhibits the binding of FITC-labeled murine M291 IgG2a and unlabeled M291. The affinity of HuM291 for CD3 is estimated to be approximately 2-3 times that of M291. Scatchard analysis revealed that the apparent affinity of HuM291-Fos was approximately Ka=1.1 nM.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human CD3
- Species Reactivity
- Human
- Clone
- HuM291
- Applications
- Inhib, FC
- Related Disease
- Cancers
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Inhibition and Flow Cytometry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
- Gene ID
- 12501
- UniProt ID
- A6H6M1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibodies
Mouse Antibodies
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Blocking Antibodies
IgG Antibodies
ScFv Antibodies
Fab Antibodies
Single Domain Antibodies
Agonistic Antibodies
NHP Antibodies
ScFv-Fc Chimeras
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CL | Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-118CL) | ELISA | Fab fragment |
| TAB-075LC | Human Anti-CD3 Recombinant Antibody (TAB-075LC) | ELISA, FC | Humanized antibody |
| TAB-076LC | Human Anti-CD3 Recombinant Antibody (TAB-076LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-077LC | Human Anti-CD3 Recombinant Antibody (TAB-077LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-078LC | Human Anti-CD3 Recombinant Antibody (TAB-078LC) | ELISA, FC, FuncS | Human IgG1, κ |
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