Mouse Anti-CD3 Recombinant Antibody (HPAB-1630LY) (CAT#: HPAB-1630LY)
The OKT3 antibody recognizes an extracellular conformational epitope on the ~20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex. This complex is present on approximately 95% of mature T cells and NKT cells, and to a varying extent on thymocytes. Additionally, a majority of T cell neoplasms also express CD3. CD3 is a dimer composed of CD3γ, δ, ε, η, and ζ subunits, which are type 1 transmembrane proteins structurally related to the immunoglobulin superfamily. CD3 forms a non-covalent association with the TCR, playing a role in transmitting antigen recognition signals to the cytoplasm of T cells and regulating T cell activation and TCR expression on the cell surface.
Specific Inquiry
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human CD3
- Species Reactivity
- Human
- Applications
- FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Flow Cytometry: 0.25 µg/test
Target
- Alternative Names
- Cluster of differentiation 3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0202MC | Rat Anti-CD3 Recombinant Antibody (clone 17A2) | FC, IHC, IP, Activ, CMCD, Depletion | Rat IgG2b, κ |
| MOB-0271MZ | Mouse Anti-CD3 Recombinant Antibody (clone G8.2.38 (1).) | IHC | Mouse IgG1 |
| FAMAB-0043CQ | Mouse Anti-CD3 Recombinant Antibody (clone 898H2-6-15) | ELISA, FuncS | Mouse IgG2a, κ |
| FAMAB-0044CQ | Mouse Anti-CD3 Recombinant Antibody (clone FN18) | ELISA, WB, FC, FuncS | Mouse IgG, κ |
| HPAB-0672LY | Mouse Anti-CD3 Recombinant Antibody (HPAB-0672LY) | ELISA, FC | Mouse IgG1 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0422CL | Mouse Anti-CD3 Recombinant Antibody (TAB-0422CL) | ELISA | Mouse IgG |
| TAB-073LC | Mouse Anti-CD3 Recombinant Antibody (TAB-073LC) | ELISA, FC | Mouse IgG |
| TAB-074LC | Mouse Anti-CD3 Recombinant Antibody (TAB-074LC) | ELISA, FC | Mouse IgG |
| TAB-097LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-097LC-F(E)) | ELISA, SPR | Mouse Fab |
| TAB-099LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-099LC-F(E)) | ELISA, SPR | Mouse Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0417CL-S(P) | Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment | ELISA, FC, FuncS | Chimeric (mouse/human) |
| TAB-0417CL-F(E) | Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment | ELISA, FC, FuncS | Chimeric (mouse/human) |
| TAB-071LC | Anti-Human CD3 Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-072LC | Chimeric Anti-Human CD3 Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-071LC-S(P) | Anti-Human CD3 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-079LC | Human Anti-CD3 Recombinant Antibody (TAB-079LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-080LC | Human Anti-CD3 Recombinant Antibody (TAB-080LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-081LC | Human Anti-CD3 Recombinant Antibody (TAB-081LC) | ELISA, FC | Human IgG1, κ |
| TAB-083LC | Human Anti-CD3 Recombinant Antibody (TAB-083LC) | ELISA, FC | Human IgG1, κ |
| TAB-084LC | Human Anti-CD3 Recombinant Antibody (TAB-084LC) | ELISA | Humanized IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-339CQ | Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) | FC, Block, IHC-Fr, IF, WB | Mouse IgG2a |
| NEUT-340CQ | Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) | FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block | Mouse IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0667LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0667LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0668LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0668LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0669LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0669LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0670LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0670LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0671LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0671LY-F(E)) | ELISA, FC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1909LY-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-1909LY-S(P)) | ELISA, FC | Humanized scfv |
| HPAB-1101-CN-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-1101-CN-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0441-YJ-S(P) | Mouse Anti-CD3 Recombinant Antibody (clone m3E3); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-1526WJ-S(P) | Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (clone 1D10) | ELISA, WB, FC | Mouse scFv |
| HPAB-1527WJ-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (clone h1D10) | ELISA, WB, FC | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0378-YC | Recombinant Llama Anti-CD3 Single Domain Antibody (A30228) | ELISA, FC | Llama VHH |
| HPAB-M0379-YC | Recombinant Llama Anti-CD3 Single Domain Antibody (A30311) | ELISA, FC | Llama VHH |
| HPAB-1029WJ | Recombinant Camelid Anti-CD3 Single Domain Antibody | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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