Mouse Anti-CD3 Recombinant Antibody (HPAB-1630LY) (CAT#: HPAB-1630LY)
The OKT3 antibody recognizes an extracellular conformational epitope on the ~20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex. This complex is present on approximately 95% of mature T cells and NKT cells, and to a varying extent on thymocytes. Additionally, a majority of T cell neoplasms also express CD3. CD3 is a dimer composed of CD3γ, δ, ε, η, and ζ subunits, which are type 1 transmembrane proteins structurally related to the immunoglobulin superfamily. CD3 forms a non-covalent association with the TCR, playing a role in transmitting antigen recognition signals to the cytoplasm of T cells and regulating T cell activation and TCR expression on the cell surface.
Specific Inquiry
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human CD3
- Species Reactivity
- Human
- Applications
- FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Flow Cytometry: 0.25 µg/test
Target
- Alternative Names
- Cluster of differentiation 3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
Recombinant Antibody
Mouse Antibody
Chimeric Antibody
Blocking Antibody
scFv Fragment Antibody
Fab Fragment Antibody
Single-domain Antibody
Agonistic Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CL | Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-118CL) | ELISA | Fab fragment |
| TAB-075LC | Human Anti-CD3 Recombinant Antibody (TAB-075LC) | ELISA, FC | Humanized antibody |
| TAB-076LC | Human Anti-CD3 Recombinant Antibody (TAB-076LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-077LC | Human Anti-CD3 Recombinant Antibody (TAB-077LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-078LC | Human Anti-CD3 Recombinant Antibody (TAB-078LC) | ELISA, FC, FuncS | Human IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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