Mouse Anti-CD3 Recombinant Antibody (HPAB-1630LY) (CAT#: HPAB-1630LY)

The OKT3 antibody recognizes an extracellular conformational epitope on the ~20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex. This complex is present on approximately 95% of mature T cells and NKT cells, and to a varying extent on thymocytes. Additionally, a majority of T cell neoplasms also express CD3. CD3 is a dimer composed of CD3γ, δ, ε, η, and ζ subunits, which are type 1 transmembrane proteins structurally related to the immunoglobulin superfamily. CD3 forms a non-covalent association with the TCR, playing a role in transmitting antigen recognition signals to the cytoplasm of T cells and regulating T cell activation and TCR expression on the cell surface.

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Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • Human CD3
  • Species Reactivity
  • Human
  • Applications
  • FC, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Flow Cytometry: 0.25 µg/test

Target

  • Alternative Names
  • Cluster of differentiation 3

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CD3"

Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-0417CL Chimeric Anti-Human CD3 Recombinant Antibody ELISA, FC, FuncS Chimeric (mouse/human)
TAB-071LC Anti-Human CD3 Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-072LC Chimeric Anti-Human CD3 Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-071LC-F(E) Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)
TAB-072LC-F(E) Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)

Blocking Antibody

CAT Product Name Application Type
NEUT-339CQ Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) FC, Block, IHC-Fr, IF, WB Mouse IgG2a
NEUT-340CQ Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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