Mouse Anti-CD3 Recombinant Antibody (HPAB-1630LY) (CAT#: HPAB-1630LY)
The OKT3 antibody recognizes an extracellular conformational epitope on the ~20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex. This complex is present on approximately 95% of mature T cells and NKT cells, and to a varying extent on thymocytes. Additionally, a majority of T cell neoplasms also express CD3. CD3 is a dimer composed of CD3γ, δ, ε, η, and ζ subunits, which are type 1 transmembrane proteins structurally related to the immunoglobulin superfamily. CD3 forms a non-covalent association with the TCR, playing a role in transmitting antigen recognition signals to the cytoplasm of T cells and regulating T cell activation and TCR expression on the cell surface.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human CD3
- Species Reactivity
- Human
- Applications
- FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Flow Cytometry: 0.25 µg/test
Target
- Alternative Names
- Cluster of differentiation 3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0416CL | Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) | FC, IB, ELISA | |
| TAB-0422CL | Mouse Anti-CD3 Recombinant Antibody (TAB-0422CL) | ELISA | Mouse IgG |
| TAB-0365CL-S(P) | Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) | IP, IB, FuncS | |
| TAB-097LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-097LC-F(E)) | ELISA, SPR | Mouse Fab |
| TAB-540CT-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-540CT-F(E)) | ELISA, FC | Mouse Fab |
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