Recombinant Anti-CD38 Biparatopic Antibody, Asymmetric sdAb-Fab (CAT#: VS-0525-YC12)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• Human CD38

• Species Reactivity
• Human

• Type
• Asymmetric sdAb-Fab

• Valency
• 1 + 1

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, Inhib

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• CD38 Molecule

• Introduction
• The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia.

• Alternative Names
• ADPRC1; cADPR1; ADPRC 1

• Gene ID
• 952

• UniProt ID
• P28907

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