Afuco™ Anti-CD4 ADCC Recombinant Antibody (Zanolimumab), ADCC Enhanced (CAT#: AFC-TAB-039)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD4. Zanolimumab (expected trade name HuMax-CD4) is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11/if_selected.jpg
Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Zanolimumab
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Trade name
- Humax-Cd4
- Generic Name
- Zanolimumab
- Related Disease
- Cutaneous T cell lymphoma (CTCL)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Zanolimumab; humax-cd4; 652153-01-0; 6G5.2; HuMax-CD4; CD4; CD4 molecule; CD4 antigen (p55), T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
- Gene ID
- 920
- UniProt ID
- P01730
Related Resources
Please refer to Zanolimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Zanolimumab.
Primary Immunodeficiency
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Zanolimumab"
Anti-Human CD4 Recombinant Antibody (Zanolimumab)Recombinant monoclonal antibody to CD4. Zanolimumab (expected trade name HuMax-CD4) is a human monoclonal antibody and an immunosuppressive drug. It is being developed for the treatment of rheumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
See other products for "CD4"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-260 | Anti-Human CD4 Recombinant Antibody (Tregalizumab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG1 - kappa |
| TAB-146 | Anti-Human CD4 Recombinant Antibody (Ibalizumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG4 - kappa |
| TAB-161LC | Anti-Human CD4 Recombinant Antibody (gOKT4A-4) | ELISA | Humanized antibody |
| TAB-168LC | Anti-Human CD4 Recombinant Antibody (TRX1) | ELISA | Humanized antibody |
| TAB-171LC | Human Anti-CD4 Recombinant Antibody (TAB-171LC) | ELISA, FC, SPR | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-171 | Anti-Human CD4 Recombinant Antibody (Keliximab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 - lambda |
| TAB-732 | Anti-CD4 Recombinant Antibody (Clenoliximab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 - lambda |
| TAB-170LC | Human Anti-CD4 Recombinant Antibody (TAB-170LC) | ELISA, FC, ADCC, CDC, SPR | Chimeric antibody (rat/human) |
| TAB-167LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (cM-T412) | ELISA | Chimeric antibody (mouse/human) |
| TAB-170LC-S(P) | Rat Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-170LC-S(P)) | ELISA, SPR | Rat scFv |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G078E | Anti-CD4 immunotoxin M-T151 (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-G078R | Anti-CD4 immunotoxin M-T151 (IgG)-RTA | Cytotoxicity assay, Function study |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-033 | Human Anti-CD4 Recombinant Antibody (clone 17b); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-034 | Mouse Anti-CD4 Recombinant Antibody (clone 2D5); Fab Fragment | Neut, ELISA, FuncS | Mouse Fab |
| PFBL-035 | Mouse Anti-CD4 Recombinant Antibody (clone Q425); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| PFBL-423 | Human Anti-CD4 Recombinant Antibody (clone 576); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-424 | Human Anti-CD4 Recombinant Antibody (clone Hu5A8); Fab Fragment | Block, Neut | Human Fab |
Mouse Antibody
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-025LC | Recombinant Anti-Human CD4 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0272MZ | Mouse Anti-CD4 Recombinant Antibody (clone 5C13) | IHC | Mouse IgG1 |
| HPAB-0302LY | Human Anti-CD4 Recombinant Antibody (clone TNX-355) | ELISA | Humanized IgG4 |
| HPAB-0303LY | Human Anti-CD4 Recombinant Antibody (clone G4H) | ELISA | Humanized IgG4 |
| HPAB-0304LY | Human Anti-CD4 Recombinant Antibody (clone G4D) | ELISA | Humanized IgG4 |
| HPAB-0305LY | Human Anti-CD4 Recombinant Antibody (clone MV1) | ELISA | Humanized IgG4 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-351CQ | Mouse Anti-CD4 Recombinant Antibody (clone 10C12) | ELISA, WB, IF, Block | Mouse IgG1 |
| NEUT-352CQ | Mouse Anti-CD4 Recombinant Antibody (clone 13B8.2) | Block, ELISA, FC, IHC-Fr, WB | Mouse IgG1, κ |
| NEUT-355CQ | Mouse Anti-CD4 Recombinant Antibody (clone RPA-T4) | FC, CyTOF, Block, IHC | Mouse IgG1, κ |
| NEUT-357CQ | Rat Anti-CD4 Recombinant Antibody (clone MAB0810) | Block, Depletion, Stim | Rat IgG2b |
| NEUT-358CQ | Rat Anti-CD4 Recombinant Antibody (clone RM4-5) | FC, CyTOF, Depletion, Block, IHC | Rat IgG2a, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-353CQ | Mouse Anti-CD4 Recombinant Antibody (clone CBL976) | FC, Neut, IF, IHC | Mouse IgG1, κ |
| NEUT-354CQ | Recombinant Mouse Anti-CD4 Antibody (CT-4) | Neut, FC, IHC, IHC-Fr, IHC-P, IP | IgG1, κ |
| NEUT-356CQ | Mouse Anti-CD4 Recombinant Antibody (clone 3-4F4) | Neut, FC, IHC, IHC-Fr, IP, ICC | Mouse IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0560 | Hi-Affi™ Rabbit Anti-CD4 Recombinant Antibody (clone DS560AB) | IHC-P | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0135CQ-S(P) | Human Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-0135CQ-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0557-WJ-S(P) | Human Anti-CD4 Recombinant Antibody (clone TRX1); scFv Fragment | ELISA | Human scFv |
| HPAB-J0044-YC-S(P) | Rat Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-J0044-YC-S(P)) | ELISA, FC, CDC | Rat scFv |
| HPAB-J0045-YC-S(P) | Rat Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-J0045-YC-S(P)) | ELISA, FC, CDC | Rat scFv |
| HPAB-J0046-YC-S(P) | Rat Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-J0046-YC-S(P)) | ELISA, FC, CDC | Rat scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-164 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Priliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-260 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Tregalizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-171 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Keliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-107 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Cedelizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-146 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Ibalizumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-TAB-039. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.