This recombinant monoclonal antibody to Human CD4 is a Human monoclonal antibody that can be used for applications: IP, Neut, ELISA.
Figure 1 Equilibrium binding data for SPR experiments
Equilibrium binding data (equilibrium binding response (Req) versus the log of the indicated protein concentrations) for SPR experiments in which sCD4, the sCD4K75T mutant, or CAP210 gp120 were injected over immobilized 21c.
Diskin, R., Marcovecchio, P. M., & Bjorkman, P. J. (2010). Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. Nature structural & molecular biology, 17(5), 608-613.
Figure 2 Sensorgrams from SPR experiments
Sensorgrams from SPR experiments in which a concentration series (from 1.0 µM-31.2 nM, two-fold dilutions) of the indicated core gp120 protein (clade C CAP210 or HIV-2 UC1) was injected together with 2 µM sCD4 (orange curves) or sCD4K75T (blue curves, thickened for clarity) over immobilized 21c Fab.
Diskin, R., Marcovecchio, P. M., & Bjorkman, P. J. (2010). Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. Nature structural & molecular biology, 17(5), 608-613.
Figure 3 Sensorgrams from SPR experiments
Sensorgrams from SPR experiments in which a concentration series (from 1.0 µM-31.2 nM, two-fold dilutions) of the indicated gp120 protein containing the V1V2 loop (CAP210V1V2 or UC1Full-length) was injected together with 2 µM sCD4 (orange curves) or sCD4K75T (blue curves) over immobilized 21c Fab.
Diskin, R., Marcovecchio, P. M., & Bjorkman, P. J. (2010). Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. Nature structural & molecular biology, 17(5), 608-613.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-164 | Anti-Human CD4 Recombinant Antibody (Priliximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
TAB-162LC | Anti-Human CD4 Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
TAB-167LC | Anti-Human CD4 Recombinant Antibody (cM-T412) | ELISA, Inhib | Chimeric antibody (mouse/human) |
TAB-170LC | Human Anti-CD4 Recombinant Antibody (TAB-170LC) | ELISA, FC, ADCC, CDC, SPR | Chimeric antibody (rat/human) |
TAB-170LC-F(E) | Human Anti-CD4 Recombinant Antibody; Fab Fragment (TAB-170LC-F(E)) | ELISA, SPR | Chimeric antibody (rat/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-146 | Anti-Human CD4 Recombinant Antibody (Ibalizumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG4 - kappa |
TAB-161LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (gOKT4A-4) | ELISA | Humanized antibody |
TAB-168LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (TRX1) | ELISA | Humanized antibody |
TAB-171LC-S(P) | Human Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-171LC-S(P)) | ELISA, SPR | Humanized scFv |
TAB-172LC-S(P) | Human Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-172LC-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G078E | Anti-CD4 immunotoxin M-T151 (IgG)-PE | Cytotoxicity assay, Function study | |
AGTO-G078R | Anti-CD4 immunotoxin M-T151 (IgG)-RTA | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-033 | Human Anti-CD4 Recombinant Antibody (clone 17b) | ELISA, Block, FC | Human IgG |
PABL-426 | Human Anti-CD4 Recombinant Antibody (clone 576) | WB, ELISA, FuncS | Human IgG |
PABL-427 | Human Anti-CD4 Recombinant Antibody (clone Hu5A8) | ELISA, Cyt, WB, Neut | Human IgG4 |
FAMAB-0007-CN | Mouse Anti-CD4 Recombinant Antibody (clone CT4) | FC | Mouse IgG |
FAMAB-0008-CN | Mouse Anti-CD4 Recombinant Antibody (clone EP96) | FC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-423 | Human Anti-CD4 Recombinant Antibody (clone 576); Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-424 | Human Anti-CD4 Recombinant Antibody (clone Hu5A8); Fab Fragment | Block, Neut | Human Fab |
HPAB-0302LY-F(E) | Human Anti-CD4 Recombinant Antibody (clone TNX-355); Fab Fragment | ELISA | Humanized Fab |
HPAB-0303LY-F(E) | Human Anti-CD4 Recombinant Antibody (clone G4H); Fab Fragment | ELISA | Humanized Fab |
HPAB-0304LY-F(E) | Human Anti-CD4 Recombinant Antibody (clone G4D); Fab Fragment | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-160LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (OKT4A) | ELISA | |
TAB-173LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (IgA F425-Alg8) | ELISA | |
TAB-174LC-S(P) | Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-174LC-S(P)) | ELISA, FC, IH | Mouse scFv |
TAB-175LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (15A7) | FC, ELISA | |
TAB-176LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (14G7) | FC, ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-025LC | Recombinant Anti-Human CD4 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-351CQ | Mouse Anti-CD4 Recombinant Antibody (clone 10C12) | ELISA, WB, IF, Block | Mouse IgG1 |
NEUT-352CQ | Mouse Anti-CD4 Recombinant Antibody (clone 13B8.2) | Block, ELISA, FC, IHC-Fr, WB | Mouse IgG1, κ |
NEUT-355CQ | Mouse Anti-CD4 Recombinant Antibody (clone RPA-T4) | FC, CyTOF, Block, IHC | Mouse IgG1, κ |
NEUT-357CQ | Rat Anti-CD4 Recombinant Antibody (clone MAB0810) | Block, Depletion, Stim | Rat IgG2b |
NEUT-358CQ | Rat Anti-CD4 Recombinant Antibody (clone RM4-5) | FC, CyTOF, Depletion, Block, IHC | Rat IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-353CQ | Mouse Anti-CD4 Recombinant Antibody (clone CBL976) | FC, Neut, IF, IHC | Mouse IgG1, κ |
NEUT-354CQ | Recombinant Mouse Anti-CD4 Antibody (CT-4) | Neut, FC, IHC, IHC-Fr, IHC-P, IP | IgG1, κ |
NEUT-356CQ | Mouse Anti-CD4 Recombinant Antibody (clone 3-4F4) | Neut, FC, IHC, IHC-Fr, IP, ICC | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0560 | Hi-Affi™ Rabbit Anti-CD4 Recombinant Antibody (clone DS560AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0758-CN-S(P) | Human Anti-CD4 Recombinant Antibody (clone Variant B); scFv Fragment | ELISA, FC | Human scFv |
HPAB-0759-CN-S(P) | Human Anti-CD4 Recombinant Antibody (clone Variant D); scFv Fragment | ELISA, FC | Human scFv |
HPAB-0302LY-S(P) | Human Anti-CD4 Recombinant Antibody (clone TNX-355); scfv Fragment | ELISA | Humanized scfv |
HPAB-0557-WJ-S(P) | Human Anti-CD4 Recombinant Antibody (clone TRX1); scFv Fragment | ELISA | Human scFv |
HPAB-0558-WJ-S(P) | Human Anti-CD4 Recombinant Antibody (clone 6G5); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-039 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Zanolimumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-164 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Priliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-260 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Tregalizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-171 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Keliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-107 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Cedelizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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