Afuco™ Anti-CD79B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-897)
CAT#: AFC-TAB-897
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human CD79B.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/1889_C4_3_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra and weak to moderate in reaction center cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows distinct cytoplasmic positivity in cells of the germinal center corona.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9751/ihc_selected.jpg
Normal Tissue
Figure 4 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to Nucleoplasm &
Plasma membrane & Cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/48_C6_1_blue_red_green.jpg
Normal Tissue
Figure 5 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to Nucleoplasm &
Plasma membrane & Cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/47_C6_1_blue_red_green.jpg
Normal Tissue
Figure 6 Colon
Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44107/169682_A_8_3.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44107/169682_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007312-CD79B
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Generic Name
- Polatuzumab
- Related Disease
- Chronic lymphocytic leukemia (CLL)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Signaling Pathways
BCR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CD79B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-897 | Humanized Anti-CD79B Recombinant Antibody (TAB-897) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Humanized (from mouse) IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0581 | Hi-Affi™ Rabbit Anti-CD79B Recombinant Antibody (clone DS581AB) | WB, IHC, ICC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1918 | PE-A*02:01/Human CD79B (LLSAEPVPA) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0058YC | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16) | FuncS | Hamster IgG |
| HPAB-618-FY | Human Anti-CD79B Recombinant Antibody (HPAB-618-FY) | FC, ELISA | Human IgG |
| HPAB-619-FY | Human Anti-CD79B Recombinant Antibody (HPAB-619-FY) | FC, ELISA | Humanized IgG |
| HPAB-1491-FY | Human Anti-CD79B Recombinant Antibody (HPAB-1491-FY) | ELISA, WB | Human IgG1 |
| FAMAB-1085CQ | Mouse Anti-CD79B Recombinant Antibody (clone B29/123) | WB, IHC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0058-YC-S(P) | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16); scFv Fragment | FuncS | Hamster scFv |
| HPAB-618-FY-S(P) | Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-618-FY-S(P)) | FC, ELISA | Humanized scFv |
| HPAB-N0044-YC-S(P) | Human Anti-CD79b Recombinant Antibody; scFv Fragment (HPAB-N0044-YC-S(P)) | FuncS | Humanized scFv |
| HPAB-1938-FY-S(P) | Mouse Anti-CD79B Recombinant Antibody scFv Fragment (HPAB-1938-FY-S(P)) | ELISA, FC, FuncS | Mouse scFv |
| HPAB-1939-FY-S(P) | Human Anti-CD79B Recombinant Antibody scFv Fragment (HPAB-1939-FY-S(P)) | ELISA, FC, FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0058-YC-F(E) | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16); Fab Fragment | FuncS | Hamster Fab |
| HPAB-1491-FY-S(P) | Human Anti-CD79B Recombinant Antibody scFv Fragment (HPAB-1491-FY-S(P)) | ELISA, WB | Human scFv |
| HPAB-J0055-YC-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0055-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
| HPAB-J0056-YC-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0056-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
| HPAB-J0057-YC-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0057-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY72 | CytoStream™ Mouse Anti-CD79B Recombinant Antibody (clone CB3-1) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY74 | Human Anti-CD79B (clone P2C2) scFv-Fc Chimera | IA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC74 | Recombinant Anti-CD79B Vesicular Antibody, EV Displayed (VS-0425-YC74) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1222 | Anti-Mouse CD79B Immunohistochemistry Kit | IHC |
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