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    Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16); Fab Fragment (CAT#: FAMAB-0058-YC-F(E))

    Antibodies against human CD79, as well as those coupled to potent cytotoxic agents, are effective at killing human B cell lymphoma cells both in vitro and in mouse chimeras. Anti-mouse CD79 mAbs have also been shown to be effective in depleting B cells and at ameliorating autoimmune disease in MRL/lpr mice. Provided is a hamster anti-mouse CD79B antibody.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line REH
    Figure 1 IF staining of human cell line REH
    (Immunofluorescent staining of human cell line REH shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/1889_C4_3_selected.jpg
    Figure 2 IHC staining of human lymph node
    Figure 2 IHC staining of human lymph node
    (Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra and weak to moderate in reaction center cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/ihc_selected.jpg
    Figure 3 IHC staining of human lymph node
    Figure 3 IHC staining of human lymph node
    (Immunohistochemical staining of human lymph node shows distinct cytoplasmic positivity in cells of the germinal center corona.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9751/ihc_selected.jpg
    Normal Tissue
    Figure 4 IF staining of human cell line A-431
    Figure 4 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to Nucleoplasm &
    Plasma membrane & Cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/48_C6_1_blue_red_green.jpg
    Figure 5 IF staining of human cell line U-2 OS
    Figure 5 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to Nucleoplasm &
    Plasma membrane & Cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/47_C6_1_blue_red_green.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Mucosal lymphoid cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44107/169682_A_8_3.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44107/169682_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
    Figure 8 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007312-CD79B

    Specifications

    • Host Species
    • Hamster
    • Type
    • Hamster Fab
    • Specificity
    • Mouse Cd79b
    • Species Reactivity
    • Mouse
    • Clone
    • HM79-16
    • Applications
    • FuncS

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • B29; Igb; Igbeta; Ig-beta

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    See other products for "CD79B"

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    Please select product type
    Humanized Antibodies IgG Antibodies Rabbit Monoclonal Antibodies MHC Tetramers for Cancer ScFv Antibodies Fab Antibodies ADCC Enhanced Antibodies FC Reagents & Kits ScFv-Fc Chimeras Extracellular Vesicle Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    TAB-897 Humanized Anti-CD79B Recombinant Antibody (TAB-897) Neut, ELISA, IF, IP, FuncS, FC, ICC Humanized (from mouse) IgG1, κ

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