Rabbit Anti-CD8A Recombinant Antibody (VS-1225-XY63)
CAT#: VS-1225-XY63
It serves as a key research tool targeting CD8A, supporting cellular and molecular experiments. This antibody performs consistently in ELISA, WB, and IHC for CD8A detection and localization.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37756/1373_A3_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37756/1492_D3_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37756/1377_A3_1_blue_red_green.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12/97_A_7_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000153563-CD8A
❮
❯
Specifications
- Host Animal
- Rabbit
- Applications
- IHC
- Specificity
- CD8A
- Target
- CD8A
- Species Reactivity
- Human
- Type
- Rabbit IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- Tris with BSA
- Preservative
- <0.1% sodium azide
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.
- Alternative Names
- CD8, p32, Leu2, IMD116, CD8alpha
- Gene ID
- 925
- UniProt ID
- P01732
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| MHH-184 | Recombinant Human Anti-human CD8A Antibody | IP, IF, FuncS | IgG |
| CAT | Product Name | Application | Type |
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| MHH-184-F(E) | Recombinant Human Anti-human CD8A Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| PFBZ-144 | Rat Anti-CD8A Recombinant Antibody (clone YTS 105.18); Fab Fragment | Neut | Rat Fab |
| CAT | Product Name | Application | Type |
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| PSBZ-144 | Rat Anti-CD8A Recombinant Antibody (clone YTS 105.18); scFv Fragment | Neut | Rat scFv |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| TAB-346LC | Anti-Human CD8A Recombinant Antibody (2.43) | FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-345LC-S(P) | Anti-Mouse CD8A Recombinant Antibody scFv Fragment (YTS169) | FC |
| CAT | Product Name | Application | Type |
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| TAB-346LC-S(P) | Anti-Human CD8A Recombinant Antibody scFv Fragment (2.43) | FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-345LC-F(E) | Anti-Mouse CD8A Recombinant Antibody Fab Fragment (YTS169) | FC |
| CAT | Product Name | Application | Type |
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| MOB-0512CT | Recombinant Mouse anti-Human CD8A Monoclonal antibody (IJU9b) | FC |
| CAT | Product Name | Application | Type |
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| NEUT-428CQ | Mouse Anti-CD8A Recombinant Antibody (clone UCHT4) | FC, IHC-Fr, IHC-P, IP, Separation, Block | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
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| NEUT-429CQ | Mouse Anti-CD8A Recombinant Antibody (clone CT-8) | Neut, FC, IHC, IHC-Fr, IHC-P, IP, ICC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-430CQ | Mouse Anti-CD8A Recombinant Antibody (clone LT8) | WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
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| NEUT-431CQ | Rat Anti-CD8A Recombinant Antibody (clone 53-6.7) | ICC, IF, FC, IHC-Fr, IP, FuncS, Block | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-432CQ | Rat Anti-CD8A Recombinant Antibody (clone MAB0811) | Block, Depletion | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-433CQ | Mouse Anti-CD8A Recombinant Antibody (clone 76-2-11) | Neut, FC, IHC-Fr, IHC-P, IP | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-434CQ | Mouse Anti-Cd8a Recombinant Antibody (clone OX-8) | WB, Neut, FC, IHC, IHC-Fr, IHC-P, IP, CyTOF® | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0582 | Hi-Affi™ Rabbit Anti-CD8A Recombinant Antibody (clone DS582AB) | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0589 | Hi-Affi™ Rabbit Anti-CD8A Recombinant Antibody (clone DS589AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0590 | Hi-Affi™ Rabbit Anti-CD8A Recombinant Antibody (clone DS590AB), PE | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0188-CN | Mouse Anti-CD8A Recombinant Antibody (HPAB-0188-CN) | FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0188-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody; scFv Fragment (HPAB-0188-CN-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0189-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody; scFv Fragment (HPAB-0189-CN-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0188-CN-F(E) | Mouse Anti-CD8A Recombinant Antibody; Fab Fragment (HPAB-0188-CN-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0189-CN-F(E) | Mouse Anti-CD8A Recombinant Antibody; Fab Fragment (HPAB-0189-CN-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0041-CN | Mouse Anti-CD8A Recombinant Antibody (clone 13C5) | WB, IP, IF | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0057-FY | Rabbit Anti-CD8A Recombinant Antibody (clone AFY0028) | ICC, IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-1024-XY114 | Mouse Anti-NHP CD8A Recombinant Antibody (clone T8/209) | ELISA | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY112 | Rat Anti-NHP CD8A Recombinant Antibody (clone YTC182.20) | FC | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY78 | CytoStream™ Mouse Anti-CD8A Recombinant Antibody (VS-0225-XY78) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY79 | CytoStream™ Mouse Anti-CD8A Recombinant Antibody (clone SK1) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
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| VS-0325-XY375 | Anti-CD8A Immunohistochemistry Kit | IHC |
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| VS-0425-YC377 | Recombinant Anti-CD8A Vesicular Antibody, EV Displayed (VS-0425-YC377) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
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| VS-0525-XY1238 | Anti-Mouse CD8A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY1237 | Anti-Human CD8A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY1240 | Anti-Rat CD8A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| VS-1225-XY60 | Mouse Anti-CD8A Recombinant Antibody (VS-1225-XY60) | FC, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY61 | Mouse Anti-CD8A Recombinant Antibody (VS-1225-XY61) | WB, IHC, FC, IP | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY62 | Mouse Anti-CD8A Recombinant Antibody (VS-1225-XY62) | IHC, ICC, IF, FC, ELISA | Mouse IgG1 |
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