Mouse Anti-CDH1 Recombinant Antibody (PABJ-0035)
CAT#: PABJ-0035
This product is a mouse antibody that recognizes human CDH1. CDH1 is involved in mechanisms regulating intercellular adhesion, mobility, and proliferation of epithelial cells. Diseases associated with CDH1 include diffuse gastric and lobular breast cancer syndromes and palpebral labial syndrome 1. This antibody has an activating effect on CDH1 and binds to the EC1-2 epitope of CDH1.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, the Golgi apparatus & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28364/672_E7_2_selected.jpg
Normal Tissue
Figure 2 ParaThyroid gland
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4812/158154_A_3_8_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_5.jpg
Normal Tissue
Figure 1 Urinary bladder
Urothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_5_5.jpg
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (BEWO, CACO-2, CAPAN-2, HaCaT, hTCEpi, MCF7, OE19, RT4, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000039068-CDH1
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human CDH1
- Species Reactivity
- Human
- Applications
- ELISA
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- CDH1; cadherin 1; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324; E-cadherin; cadherin-1; CAM 120/80; E-cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial; cell-CAM 120/80; epididymis secretory sperm binding protein; epithelial cadherin; uvomorulin
- Gene ID
- 999
- UniProt ID
- P12830
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| HPAB-0464-WJ-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.6); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0465-WJ-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.15); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0466-WJ-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.17); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0467-WJ-F(E) | Human Anti-CDH1 Recombinant Antibody (clone hSC10.17); Fab Fragment | ELISA, FC | Humanized Fab |
| PABJ-0035-F(E) | Mouse Anti-CDH1 Recombinant Antibody Fab Fragment (PABJ-0035-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
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| HPAB-0464-WJ-S(P) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.6); scFv Fragment | ELISA, FC | Mouse scFv |
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| HPAB-0466-WJ-S(P) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.17); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0467-WJ-S(P) | Human Anti-CDH1 Recombinant Antibody (clone hSC10.17); scFv Fragment | ELISA, FC | Humanized scFv |
| PABJ-0035-S(P) | Mouse Anti-CDH1 Recombinant Antibody scFv Fragment (PABJ-0035-S(P)) | ELISA | Mouse scFv |
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