Human Anti-CDH17 Recombinant Antibody (clone D2106) (CAT#: HPAB-2066LY)

Figure 1 Competition assay of the hybridoma culture supernatant.

All of the data shown are the means-standard deviations of triplicate assays.

Kusano-Arai, O., Iwanari, H., Kudo, S., Kikuchi, C., Yui, A., Akiba, H.,... & Hamakubo, T. (2018). Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 1-11.

Figure 2 Specific binding to the cell surface CDH17 was demonstrated by flow cytometry.

The filled histograms indicate anti-CDH17 mAbs, and the open histograms indicate control IgG binding to AGS cells (upper panels) and MKN74 cells (lower panels). The numbers at the top designate the clone number of the anti-CDH17 mAbs. CDH17, Cadherin-17; mAb, monoclonal antibody.

Kusano-Arai, O., Iwanari, H., Kudo, S., Kikuchi, C., Yui, A., Akiba, H.,... & Hamakubo, T. (2018). Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 1-11.

Figure 3 Dose-dependent binding of the anti-CDH17 mAbs.

All of the data shown are the means-standard deviations of triplicate assay.

Kusano-Arai, O., Iwanari, H., Kudo, S., Kikuchi, C., Yui, A., Akiba, H.,... & Hamakubo, T. (2018). Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17. Monoclonal antibodies in immunodiagnosis and immunotherapy, 37(1), 1-11.