Anti-CEACAM1 (clone W24V173) Recombinant Antibody Coupled Liposome (VS-1024-FY174)
CAT#: VS-1024-FY174
This specialized type of liposome is designed to target the CEACAM1 protein, which is critically involved in the progression and metastasis of melanoma. By selectively delivering therapeutic agents to cells expressing CEACAM1, these liposomes can significantly improve the precision of drug delivery, ensuring that treatments are directed primarily at cancerous cells while sparing healthy tissue. As a result, this targeted approach has the potential to enhance the overall effectiveness of melanoma therapies, leading to better patient outcomes and reduced side effects.
Gene Expression
Normal Tissue
Figure 1 Colon
Enterocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_8_3.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2146/5911_A_9_5.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (CAPAN-2, Hep G2, OE19, RT4, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000079385-CEACAM1
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More Infomation
Specifications
- Potential Clinical Applications
- Melanoma
Product Composition
- Clone
- W24V173
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant mouse monoclonal antibody that was specifically designed to bind to the cell adhesion molecule CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1). CEACAM1 is known for its involvement in various cellular processes, including cell adhesion, immune response modulation, and tumor progression.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- CEACAM1
- Introduction
- This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
- Alternative Names
- CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; BGP1; BGPI; carcinoembryonic antigen-related cell adhesion molecule 1; antigen CD66; CD66a antigen
- Full Name
- Carcinoembryonic Antigen Related Cell Adhesion Molecule 1
- Gene ID
- 634
- UniProt ID
- P13688
- Sequence Similarities
- Belongs to the immunoglobulin superfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Phosphorylated on serine and tyrosine
- Protein Refseq
- XP_011525508.1; XP_054177686.1; NP_001020083.1; NP_001171742.1; NP_001171744.1
- Function
- Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity).
Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesis.
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Datasheet
MSDS
COA
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- Product Name
See other products for "CEACAM1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1253z | Mouse Anti-CEACAM1 Recombinant Antibody (clone 23A3) | ELISA, IHC, WB | Mouse IgG1, κ |
| MOB-2493MZ | Recombinant Mouse Anti-Human CEACAM1 Antibody (clone 2207) | ELISA, IP, RIA | Mouse antibody |
| HPAB-0470-CN | Mouse Anti-CEACAM1 Recombinant Antibody (HPAB-0470-CN) | ELISA, FC | Mouse IgG |
| HPAB-0471-CN | Mouse Anti-CEACAM1 Recombinant Antibody (clone 18-20) | ELISA, FC | Mouse IgG |
| FAMAB-1026CQ | Human Anti-CEACAM1 Recombinant Antibody (clone C5-1X/8) | WB, ELISA, IHC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-014-F(E) | Anti-Human CEA Recombinant Antibody Fab Fragment (Arcitumomab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | Fab' - G1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-156CL | Human Anti-CEACAM1 Recombinant Antibody (TAB-156CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-439LC | Human Anti-CEACAM1 Recombinant Antibody (TAB-439LC) | ELISA, FC, IF | Human IgG |
| TAB-439LC-S(P) | Human Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-439LC-S(P)) | IF, FC, ELISA | Human scFv |
| TAB-439LC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-439LC-F(E)) | IF, FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-443LC | Human Anti-CEACAM1 Recombinant Antibody (TAB-443LC) | Block, Cyt, ELISA, FC, FuncS | Chimeric (Mouse/Human) IgG1, κ |
| TAB-443LC-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-443LC-S(P)) | FC, SPR, IHC, ELISA | Mouse scFv |
| TAB-443LC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-443LC-F(E)) | FC, SPR, IHC, ELISA | Chimeric (Mouse/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-453CQ | Mouse Anti-Ceacam1 Recombinant Antibody (clone MAb-CC1) | FC, WB, IP, IHC, ELISA, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-454CQ | Mouse Anti-Ceacam1 Recombinant Antibody (clone CC1) | WB, Neut, FC, FuncS, IHC, IHC-Fr, IHC-P, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0648 | Hi-Affi™ Rabbit Anti-CEACAM1 Recombinant Antibody (clone DS648AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (HPAB-0470-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0471-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (clone 18-20) | ELISA, FC | Mouse scFv |
| HPAB-0472-CN-S(P) | Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (clone 6G5J) | ELISA, FC | Mouse scFv |
| HPAB-0372-YC-S(P) | Human Anti-CEACAM1 Recombinant Antibody; scFv Fragment (HPAB-0372-YC-S(P)) | ELISA, FC, Activ | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0470-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (HPAB-0470-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0471-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (clone 18-20) | ELISA, FC | Mouse Fab |
| HPAB-0472-CN-F(E) | Mouse Anti-CEACAM1 Recombinant Antibody; Fab Fragment (clone 6G5J) | ELISA, FC | Mouse Fab |
| HPAB-0372-YC-F(E) | Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (HPAB-0372-YC-F(E)) | ELISA, FC, Activ | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0572CQ | Rat Anti-CEACAM1 Recombinant Antibody (clone YTH71.3) | ELISA | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0517 | PE-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0518 | APC-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0519 | FITC-B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC | |
| MHC-CN0520 | B*07:02/Human CEACAM1 (LPVSPRLQL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC150 | Recombinant Anti-CEACAM1 Vesicular Antibody, EV Displayed (VS-0425-YC150) | Block, Cyt, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1353 | Anti-Mouse CEACAM1 Immunohistochemistry Kit | IHC |
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