Mouse Anti-CEACAM6 Recombinant Antibody (VS3-FY2666) (CAT#: VS3-FY2666)
This incredible mouse recombinant monoclonal antibody is capable of binding to CEACAM6. The calculated molecular weight of the protein is 37.2 kDa. It exhibits cross-reactivity with human, mouse and rat. This monoclonal antibody is potential for conducting research on Cystic Fibrosis; Gastrointestinal Carcinoma. The antibody can be utilized for detection of CEACAM6 by Western Blot, Immunohistochemistry, Immunocytochemistry, Flow cytometry, ELISA.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/ihc_selected.jpg
(Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/ihc_selected.jpg
Figure 2 High expression in lung.
(Macrophages Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_3_4.jpg
(Macrophages Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_3_4.jpg
Figure 3 Colon
(Enterocytes - Microvilli Staining: Medium Intensity: Moderate Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_9_3.jpg
(Enterocytes - Microvilli Staining: Medium Intensity: Moderate Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_9_3.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_8_8.jpg
Figure 5 RNA cell line category: Cell line enriched (OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000086548-CEACAM6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000086548-CEACAM6
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Carcinoembryonic antigen related cell adhesion molecule 6 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC, ICC, FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 37.2 kDa.
- Related Disease
- Cystic Fibrosis; Gastrointestinal Carcinoma
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/25-1/100
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Carcinoembryonic Antigen Related Cell Adhesion Molecule 6; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Non-Specific Cross Reacting Antigen); Normal Cross-Reacting Antigen; NCA; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6; Non-Specific Crossreacting Antigen
- Gene ID
- 4680
- Cellular Localization
- Cell membrane, Cell surface
- Post Translation Modifications
- Glycosylated.
Glycosylation at Asn104, Asn111, Asn115, Asn152, Asn173, Asn197, Asn224, Asn256, Asn274, Asn288, Asn292, and Asn309
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 16 sites, 6 N-linked glycans (3 sites), 1 O-linked glycan (2 sites)
- Protein Refseq
- XP_011525292.1; XP_054177043.1; NP_002474.4
- Function
- Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 oCcurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-042 | Recombinant Anti-Human CEACAM6 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-004LC-VHH | Anti-Human CEACAM6 Recombinant Antibody (TAB-004LC-VHH) | ELISA, WB, FC, Inhib, FuncS, ICC, SPR | Single domain antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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