Camelid Anti-CFTR Recombinant Single Domain Antibody (NBD-0022-YJ-VHH)
CAT#: NBD-0022-YJ-VHH
This product is a recombinant Llama single domain antibody that recognizes Human CFTR.
Gene Expression
Normal Tissue
Figure 1 High expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3_val_selected.jpg
Normal Tissue
Figure 2 Low expression in skeletal muscle.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1951/160344_B_3_6_val_selected.jpg
Normal Tissue
Figure 3 Low expression in lymph node
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_9_8_val_selected.jpg
Normal Tissue
Figure 4 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (CACO-2, MOLT-4, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000001626-CFTR
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Specifications
- Immunogen
- 2PT-NBD1, a stabilized version of human CFTR NBD1 domain bearing the mutations S492P/A534P/I539T.
- Host Species
- Camelid
- Type
- Camelid VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- NBD-0022-YJ-VHH
- Applications
- ELISA, Thermal stabilization
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This sdAb has been reported for use in Enzyme-linked Immunosorbent Assay, Thermal stabilization.
Target
- Alternative Names
- CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1; cystic fibrosis transmembrane conductance regulator; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulating; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- Gene ID
- 1080
- UniProt ID
- P13569
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CFTR"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1704z | Mouse Anti-CFTR Recombinant Antibody (clone 28C12) | WB, IF, IHC | Mouse IgG1 |
| MOB-0481CT | Recombinant Mouse anti-Human CFTR Monoclonal antibody (N4B8) | FC, IHC-Fr, IHC-P | |
| MRO-1772-CN | Rabbit Anti-CFTR Polyclonal Antibody (MRO-1772-CN) | WB, IF, IHC, FC | Rabbit IgG |
| PABS-0273 | Camelid Anti-CFTR Recombinant Antibody (PABS-0273) | Thermal shift assay (DSF), Isothermal titration microcalorimertry (ITC), Differential scanning calorimetry (DSC), FC, pull-down, ELISA, FuncS | Camelid VHH |
| PABS-0274 | Camelid Anti-CFTR Recombinant Antibody (clone G3a) | Thermal shift assay (DSF), Isothermal titration microcalorimertry (ITC), Differential scanning calorimetry (DSC), FC, Pull-down, ELISA, FuncS | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-458CQ | Mouse Anti-CFTR Recombinant Antibody (clone CF3) | Block, FC, ICC, IF, IHC, IHC-P, IP, WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NBD-0019-YJ-VHH | Camelid Anti-CFTR Recombinant Single Domain Antibody (NBD-0019-YJ-VHH) | ELISA, Thermal stabilization | Camelid VHH |
| NBD-0020-YJ-VHH | Camelid Anti-CFTR Recombinant Single Domain Antibody (NBD-0020-YJ-VHH) | ELISA | Camelid VHH |
| NBD-0021-YJ-VHH | Camelid Anti-CFTR Recombinant Single Domain Antibody (NBD-0021-YJ-VHH) | ELISA, Thermal stabilization | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY436 | Anti-CFTR Immunohistochemistry Kit | IHC | |
| VS-0525-XY1406 | Anti-Mouse CFTR Immunohistochemistry Kit | IHC | |
| VS-0525-XY1405 | Anti-Human CFTR Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC395 | Recombinant Anti-CFTR Vesicular Antibody, EV Displayed (VS-0425-YC395) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC32 | Recombinant Anti-CFTR Biparatopic Antibody, Tandem scFv | ELISA, FC, Pull-down | Tandem sdAb |
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