Human Anti-CHRNA1 Recombinant Antibody (clone 170) (CAT#: FAMAB-0327JF)
Recombinant monoclonal antibody specially binds to acetylcholine receptor. Clone 170 is a human monoclonal antibody that can strongly binding to CN21 cells. This product can be widely used in the treatment of myasthenia gravis.
Specific Inquiry
ELISA
Figure 1 The monospecificity of these mAb was confirmed by ELISA.
Hybridoma specificity against the extracellular domain of human α-subunit expressed in E. coli (α-ECD E. coli) or P.pastoris (α-ECD P. pastoris) or the intact human AChR.
FC
Figure 2 FACS analysis of anti-α-ECD human mAb (IgM) for binding to CN21 cells that express human AChR.
A non-AChRrelated human IgM was used as a negative control.
Specifications
- Host Species
- Human
- Type
- Human IgM, λ
- Specificity
- Human CHRNA1
- Species Reactivity
- Human
- Clone
- 170
- Applications
- RIA, ELISA, FuncS
- Related Disease
- Myasthenia gravis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ACHRA; ACHRD; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; SCCMS
- Gene ID
- 1134
- UniProt ID
- P02708
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 170"
See other products for "CHRNA1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1267z | Mouse Anti-CHRNA1 Recombinant Antibody (clone 25F9) | WB, ICC, IF, IHC, IP | Mouse IgG1 |
| PABZ-149 | Recombinant Rat Anti-T. californica CHRNA1 Antibody (mAb6) | WB | IgG |
| HPAB-1968-FY | Human Anti-CHRNA1 Recombinant Antibody (clone Fab332) | RIA | Human IgG, λ |
| PABS-0058 | Rat Anti-Chrna1 Recombinant Antibody (Clone Fab35) | ELISA, FuncS | Rat IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-149 | Recombinant Rat Anti-T. californica CHRNA1 Antibody Fab Fragment (mAb6) | WB | Fab |
| HPAB-1968-FY-S(P) | Human Anti-CHRNA1 Recombinant Antibody (clone Fab332); scFv Fragment | ELISA | Human scFv |
| FAMAB-0327JF-S(P) | Human Anti-CHRNA1 Recombinant Antibody (clone 170); scFv Fragment | RIA, ELISA, FuncS | Human scFv |
| PSBS-0058 | Rat Anti-Chrna1 Recombinant Antibody (Clone Fab35); scFv Fragment | ELISA, FuncS | Rat scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-149 | Recombinant Rat Anti-T. californica CHRNA1 Antibody scFv Fragment (mAb6) | WB | scFv |
| HPAB-1968-FY-F(E) | Human Anti-CHRNA1 Recombinant Antibody (clone Fab332); Fab Fragment | ELISA | Human Fab, λ |
| FAMAB-0327JF-F(E) | Human Anti-CHRNA1 Recombinant Antibody (clone 170); Fab Fragment | RIA, ELISA, FuncS | Human Fab |
| PFBS-0058 | Rat Anti-Chrna1 Recombinant Antibody (Clone Fab35); Fab Fragment | ELISA, FuncS | Rat Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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