Human Anti-Citrullinated epitope Recombinant Antibody (clone C07)
CAT#: HPAB-AP043-YC
Autoimmune reactions to certain epitopes of self antigens most likely contribute to the development of rheumatoid arthritis. Often these epitopes are citrullinated. Provided is a novel antibody C07 that can bind to certain citrullinated epitopes namely citrullinated enolase, vimentin, fibrinogen and citrullinated synthetic peptides. The antibody may also be an antibody that has reactivity against only CEP-1, CCP and cit-vim such as antibody C07. The antibody can be used in diagnostics of rheumatoid arthritis, for therapy against rheumatoid arthritis and as research tools.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human Citrullinated epitope
- Species Reactivity
- Human
- Clone
- C07
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The Citrullinated epitopes antibody has been reported in applications of Immunohistochemistry, Immunofluorescence, Enzyme-linked Immunosorbent Assay.
For Immunohistochemistry: Cells were fixed with formaldehyde and stained with murinised monoclonal ACPAs (D10, B02, C07), murinised control antibody (E02), rabbit polyclonal anti-PAD2 and monoclonal mouse anti-PADI4 followed by horseradish peroxidase conjugated antimouse antibody as a secondary antibody and 3,3-diaminobenzidene (DAB). The slides were counterstained with Mayer's haematoxylin and viewed using a light microscope.
For Immunofluorescence: The cells were incubated with the murinised ACPAs, polyclonal ACPA and anti-CD68 monoclonal antibody, followed by Alexa-Fluor-633-labeled secondary antibodies (Abcam) and counterstained with 4′,6-diamidino-2-phenylindole.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone C07"
- CAT
- Product Name
See other products for "Citrullinated epitope"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP042-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone A40) | ELISA | Human IgG |
| HPAB-AP044-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone F12) | ELISA | Human IgG |
| HPAB-AP045-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone 109) | ELISA | Human IgG |
| HPAB-AP046-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone B07) | ELISA | Human IgG |
| HPAB-AP047-YC | Human Anti-Citrullinated epitope Recombinant Antibody (clone A03) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP042-YC-S(P) | Human Anti-Citrullinated epitope Recombinant Antibody (clone A40); scFv Fragment | ELISA | Human scFv |
| HPAB-AP043-YC-S(P) | Human Anti-Citrullinated epitope Recombinant Antibody (clone C07); scFv Fragment | ELISA | Human scFv |
| HPAB-AP044-YC-S(P) | Human Anti-Citrullinated epitope Recombinant Antibody (clone F12); scFv Fragment | ELISA | Human scFv |
| HPAB-AP045-YC-S(P) | Human Anti-Citrullinated epitope Recombinant Antibody (clone 109); scFv Fragment | ELISA | Human scFv |
| HPAB-AP605-YC-S(P) | Mouse Anti-Citrullinated epitope Recombinant Antibody scFv Fragment (HPAB-AP605-YC-S(P)) | ELISA, IHC, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP042-YC-F(E) | Human Anti-Citrullinated epitope Recombinant Antibody (clone A40); Fab Fragment | ELISA | Human Fab |
| HPAB-AP043-YC-F(E) | Human Anti-Citrullinated epitope Recombinant Antibody (clone C07); Fab Fragment | ELISA | Human Fab |
| HPAB-AP044-YC-F(E) | Human Anti-Citrullinated epitope Recombinant Antibody (clone F12); Fab Fragment | ELISA | Human Fab |
| HPAB-AP045-YC-F(E) | Human Anti-Citrullinated epitope Recombinant Antibody (clone 109); Fab Fragment | ELISA | Human Fab |
| HPAB-AP046-YC-F(E) | Human Anti-Citrullinated epitope Recombinant Antibody (clone B07); Fab Fragment | ELISA | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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