Human Anti-CMV gB Vaccinal Antibody (VS-0625-XY3)
CAT#: VS-0625-XY3
A vaccinal antibody targeting CMV gB, suitable for ELISA, SPR, and neutralization (Neut) assays, features an engineered Fc segment to induce vaccine-like effects and enhance antiviral efficacy by modulating Fc-mediated functions, enabling both robust binding detection and potent viral neutralization.
Specifications
- Target
- CMV gB
- Host Animal
- Human
- Applications
- ELISA; SPR; Neut
- Specificity
- CMV gB
- Species Reactivity
- CMV
- Type
- Human IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Epitope
- Antigenic domain 2 site 1
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Human cytomegalovirus (CMV, human herpesvirus 5) is a pervasive viral pathogen and major cause of disease in infants and immunocompromised patients worldwide. One of the leading targets for vaccine development is CMV glycoprotein B (gB), which is a viral envelope protein that mediates fusion with host-cell membranes and is required for viral entry into all known cell types.
- Related Disease
- Permanent hearing loss; Cognitive impairment; Retinitis; Cerebral palsy
- Alternative Names
- Cytomegalovirus glycoprotein B
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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