Human Anti-CMV gB Vaccinal Antibody (VS-0625-XY3)

CAT#: VS-0625-XY3

A vaccinal antibody targeting CMV gB, suitable for ELISA, SPR, and neutralization (Neut) assays, features an engineered Fc segment to induce vaccine-like effects and enhance antiviral efficacy by modulating Fc-mediated functions, enabling both robust binding detection and potent viral neutralization.

Specifications

  • Target
  • CMV gB
  • Host Animal
  • Human
  • Applications
  • ELISA; SPR; Neut
  • Specificity
  • CMV gB
  • Species Reactivity
  • CMV
  • Type
  • Human IgG
  • Purity
  • >95%, determined by SDS-PAGE
  • Purification
  • Protein A purified
  • Epitope
  • Antigenic domain 2 site 1
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Target

  • Introduction
  • Human cytomegalovirus (CMV, human herpesvirus 5) is a pervasive viral pathogen and major cause of disease in infants and immunocompromised patients worldwide. One of the leading targets for vaccine development is CMV glycoprotein B (gB), which is a viral envelope protein that mediates fusion with host-cell membranes and is required for viral entry into all known cell types.
  • Related Disease
  • Permanent hearing loss; Cognitive impairment; Retinitis; Cerebral palsy
  • Alternative Names
  • Cytomegalovirus glycoprotein B
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Datasheet

MSDS

COA

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Recommended Dilution Buffer

Secondary Antibody

Isotype Control

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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