Rabbit Anti-CNTNAP1 Recombinant Antibody (clone R04-3E1) (CAT#: VS3-XY3321)
The rabbit recombinant antibody specifically recognizes CNTNAP1 (Contactin associated protein 1), which plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. It reacts with human, mouse and rat CNTNAP1. It has been tested using Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of Western Blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat CNTNAP1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R04-3E1
- Applications
- WB, IHC-P
- Related Disease
- Lethal Congenital Contracture Syndrome 7; Neuropathy, Congenital Hypomyelinating, 3
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- CHN3; P190; CASPR; NRXN4; CNTNAP
- Gene ID
- 8506
- UniProt ID
- P78357
- Long Name
- Contactin associated protein 1
- Cellular Localization
- Membrane, Cell junction
- Post Translation Modifications
- Glycosylation at Asn120, Asn128, Asn276, Asn420, Asn499, Asn518, Asn597, Asn653, Asn664, Asn763, Asn804, Asn843, Asn860, Asn948, Asn956, Asn1078, and Asn1147 (NX_P78357 [NX_P78357-1])
Modification sites at PhosphoSitePlus (P78357)
Glycosylation from GlyGen (P78357) 18 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_003623.1
- Function
- Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons.
Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers.
Demarcates the paranodal region of the axo-glial junction.
In association with contactin involved in the signaling between axons and myelinating glial cells.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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