Recombinant monoclonal antibody specially binds to cocaine. K1-2 is a mouse monoclonal antibody that can be potencially used in the treatment of cocaine addiction.
Figure 1 The fraction of molecular surface area buried upon interaction of a ligand with an antibody versus the molecular surface area of the free ligand.
Black dots represent the antibodies discussed here.
Pozharski, E., Moulin, A., Hewagama, A., Shanafelt, A. B., Petsko, G. A., & Ringe, D. (2005). Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2. Journal of molecular biology, 349(3), 570-582.
Figure 2 Immunohistochemical detection of hsp25 or hsp70i induction and cocaine adduction of cellular macromolecules in murine liver 24 hours after treatment of PB-pretreated mice.
Field original magnification ×200.
Salminen Jr, W. F., Roberts, S. M., Fenna, M., & Voellmy, R. (1997). Heat shock protein induction in murine liver after acute treatment with cocaine. Hepatology, 25(5), 1147-1153.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-224 | Recombinant Anti-cocaine Antibody | ELISA, WB, Neut, FuncS | IgG |
MHH-224 | Recombinant Human Anti-cocaine Antibody | RIA, ELISA, FuncS | IgG |
HPAB-S0162-YC | Mouse Anti-Cocaine Recombinant Antibody (clone 9A3) | ELISA | Mouse IgG |
HPAB-S0163-YC | Mouse Anti-Cocaine Recombinant Antibody (clone 19G8) | ELISA | Mouse IgG |
HPAB-S0164-YC | Mouse Anti-Cocaine Recombinant Antibody (clone 8G4G) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-224-F(E) | Recombinant Anti-cocaine Antibody Fab Fragment | FC, Neut, Funcs | Fab |
HPAB-1084-FY-S(P) | Mouse Anti-COCAINE Recombinant Antibody; scFv Fragment (HPAB-1084-FY-S(P)) | ELISA | Mouse scFv |
HPAB-S0162-YC-F(E) | Mouse Anti-Cocaine Recombinant Antibody (clone 9A3); Fab Fragment | ELISA | Mouse Fab |
HPAB-S0163-YC-F(E) | Mouse Anti-Cocaine Recombinant Antibody (clone 19G8); Fab Fragment | ELISA | Mouse Fab |
HPAB-1583WJ-F(E) | Mouse Anti-Cocaine Recombinant Antibody; Fab Fragment (clone 92H2) | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP612-YC-S(P) | Human Anti-Cocaine Recombinant Antibody (clone ch2E2); scFv Fragment | ELISA | Human scFv |
FAMAB-0306JF-S(P) | Mouse Anti-Cocaine Recombinant Antibody (clone K1-2); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
FAMAB-0307JF-S(P) | Mouse Anti-Cocaine Recombinant Antibody (clone K2-1); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
FAMAB-0308JF-S(P) | Mouse Anti-Cocaine Recombinant Antibody (clone K2-2); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
FAMAB-0309JF-S(P) | Mouse Anti-Cocaine Recombinant Antibody (clone K2-5); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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