Rabbit Anti-COL1A1 Recombinant Antibody (VS3-CJ278) (CAT#: VS3-CJ278)
This product is a rabbit antibody that recognizes COL1A1.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12111/1934_F8_3_cr5d1ca7aa8d4b0_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12111/1934_F8_3_cr5d1ca7aa8d4b0_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows extracellular positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/ihc_selected.jpg
(Immunohistochemical staining of human colon shows extracellular positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/ihc_selected.jpg
Figure 3 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12111/1936_A7_4_blue_red_green.jpg
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12111/1936_A7_4_blue_red_green.jpg
Figure 4 Cerebral cortex
(Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_B_7_5.jpg
(Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_B_7_5.jpg
Figure 5 Kidney
(Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_A_8_5.jpg
(Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_A_8_5.jpg
Figure 6 Testis
(Leydig cells
Staining:High
Intensity: Strong
Quantity: 75%-25% Preleptotene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Spermatogonia cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_A_5_6.jpg
(Leydig cells
Staining:High
Intensity: Strong
Quantity: 75%-25% Preleptotene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Spermatogonia cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_A_5_6.jpg
Figure 7 Skin
(Fibroblasts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Keratinocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_B_9_1.jpg
(Fibroblasts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Keratinocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11795/32976_B_9_1.jpg
Figure 8 RNA cell line category: Cell line enhanced (ASC TERT1, BJ, fHDF/TERT166, HSkMC, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000108821-COL1A1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000108821-COL1A1
Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Bovine COL1A1
- Species Reactivity
- Human, Bovine
- Applications
- WB, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunohistochemistry.
Target
- Alternative Names
- OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1
- Gene ID
- 1277
- UniProt ID
- P02452
- Sequence Similarities
- Belongs to the fibrillar collagen family.
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- Contains mostly 4-hydroxyproline. Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Contains 3-hydroxyproline at a few sites. This modification occurs on the first proline residue in the sequence motif Gly-Pro-Hyp, where Hyp is 4-hydroxyproline.
Lysine residues at the third position of the tripeptide repeating unit (G-X-Y) are 5-hydroxylated in some or all of the chains.
O-glycosylated on hydroxylated lysine residues. The O-linked glycan consists of a Glc-Gal disaccharide.
- Protein Refseq
- NP_000079.2
- Function
- Type I collagen is a member of group I collagen (fibrillar forming collagen).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "COL1A1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-706-VHH | Recombinant Anti-Human COL1A1 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1591CT | Recombinant Mouse anti-Human COL1A1 Monoclonal antibody (003-29) | ELISA, sELISA | |
| ZG-0167J | Mouse Anti-COL1A1 Recombinant Antibody (clone 1B2) | IHC-P, IF | Mouse IgG |
| ZG-0168J | Mouse Anti-COL1A1 Recombinant Antibody (clone 2D10) | IHC-P, IF | Mouse IgG |
| ZG-0169J | Mouse Anti-COL1A1 Recombinant Antibody (clone 4B5) | IHC-P, IF | Mouse IgG |
| ZG-0170J | Mouse Anti-COL1A1 Recombinant Antibody (clone 4H10) | IF/ICC, IHC-P | Mouse IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0754 | Hi-Affi™ Rabbit Anti-COL1A1 Recombinant Antibody (clone DS754AB) | WB, IHC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-CJ278. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.