This is a human monoclonal antibody which specifically reacts with CR1. The anti-CR1 monoclonal antibody HB8592 binds to CR1 with high affinity.
Figure 1 Immuno-precipitation assay to examine PvRBP-soluble CR1 complex formation.
An anti-CR1 monoclonal antibody HB8592 was incubated with soluble recombinant CR1 (sCR1) in the presence of either recombinant PfRH4 (right panel) or PvRBP1a and PvRBP1b (middle panel) or PvRBP2a, PvRBP2b and PvRBP2c (le panel) and protein G Sepharose (right, middle and le panels correspond to three dierent gel blots). Immuno-precipitation eluates were fractionated on SDS-PAGE and visualized using SimplyBlue SafeStain. Molecular weight markers are shown on the le-hand side in kDa for each panel. Soluble CR1 is labeled as sCR1 and the two antibody chains are labeled as Ab. I: Input, U: Unbound and E: Eluate.
Prajapati, S. K., Borlon, C., Rovira-Vallbona, E., Gruszczyk, J., Menant, S., Tham, W. H., ... & Vinetz, J. (2019). Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes. Scientific Reports, 9(1), 8943.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-240-S(P) | Recombinant Anti-human CR1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
MHH-240-S(P) | Recombinant Human Anti-human CR1 Antibody scFv Fragment | Neut, WB, FuncS | scFv |
HPAB-0421-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone E11); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-0422-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); scFv Fragment | ELISA, FC | Mouse scFv |
FAMAB-0310-CN-S(P) | Mouse Anti-CR1 Recombinant Antibody (clone HB8592); scFv Fragment | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-240 | Recombinant Human Anti-human CR1 Antibody | ELISA, IP, FuncS | IgG |
HPAB-0421-CN | Mouse Anti-CR1 Recombinant Antibody (clone E11) | ELISA, FC | Mouse IgG1 |
HPAB-0422-CN | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1) | ELISA, FC | Mouse IgG1 |
HPAB-0423-CN | Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9) | ELISA, FC | Mouse IgG1 |
HPAB-0424-CN | Human Anti-CR1 Recombinant Antibody (clone EDI3G4) | ELISA, FC | Chimeric (mouse/human) IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-240-F(E) | Recombinant Human Anti-human CR1 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
HPAB-0421-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone E11); Fab Fragment | ELISA, FC | Mouse Fab |
HPAB-0422-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1); Fab Fragment | ELISA, FC | Mouse Fab |
HPAB-0423-CN-F(E) | Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9); Fab Fragment | ELISA, FC | Mouse Fab |
HPAB-0424-CN-F(E) | Human Anti-CR1 Recombinant Antibody (clone EDI3G4); Fab Fragment | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-496CQ | Mouse Anti-CR1 Recombinant Antibody (clone J3D3) | Block, ELISA, FC, IHC-Fr, IHC-P | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0794 | Hi-Affi™ Rabbit Anti-CR1 Recombinant Antibody (clone DS794AB) | WB, IHC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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