Mouse Anti-CR1 Recombinant Antibody (clone HB8592) (CAT#: FAMAB-0310-CN)
This is a human monoclonal antibody which specifically reacts with CR1. The anti-CR1 monoclonal antibody HB8592 binds to CR1 with high affinity.
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IP
Figure 1 Immuno-precipitation assay to examine PvRBP-soluble CR1 complex formation.
An anti-CR1 monoclonal antibody HB8592 was incubated with soluble recombinant CR1 (sCR1) in the presence of either recombinant PfRH4 (right panel) or PvRBP1a and PvRBP1b (middle panel) or PvRBP2a, PvRBP2b and PvRBP2c (le panel) and protein G Sepharose (right, middle and le panels correspond to three dierent gel blots). Immuno-precipitation eluates were fractionated on SDS-PAGE and visualized using SimplyBlue SafeStain. Molecular weight markers are shown on the le-hand side in kDa for each panel. Soluble CR1 is labeled as sCR1 and the two antibody chains are labeled as Ab. I: Input, U: Unbound and E: Eluate.
Prajapati, S. K., Borlon, C., Rovira-Vallbona, E., Gruszczyk, J., Menant, S., Tham, W. H., ... & Vinetz, J. (2019). Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes. Scientific Reports, 9(1), 8943.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CR1
- Species Reactivity
- Human
- Clone
- HB8592
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay and Immunoprecipitation.
Target
- Alternative Names
- Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Knops Blood Group Antigen; C3-Binding Protein; C4BR; CD35; KN
- Gene ID
- 1378
- UniProt ID
- P17927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240 | Recombinant Anti-human CR1 Antibody | ELISA, WB, IF, FuncS | IgG |
| HPAB-0421-CN | Mouse Anti-CR1 Recombinant Antibody (clone E11) | ELISA, FC | Mouse IgG1 |
| HPAB-0422-CN | Mouse Anti-CR1 Recombinant Antibody (clone EDIVH1/VL1) | ELISA, FC | Mouse IgG1 |
| HPAB-0423-CN | Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9) | ELISA, FC | Mouse IgG1 |
| HPAB-0424-CN | Human Anti-CR1 Recombinant Antibody (clone EDI3G4) | ELISA, FC | Chimeric (mouse/human) IgG1 |
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