Rabbit Anti-CRP Recombinant Antibody (clone R09-9G4)
CAT#: VS3-XY3323
The antibody is a recombinant rabbit antibody binding to CRP (C-reactive protein), which promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It specifically reacts with human CRP. It has been detected by Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation is 1/500-1/1000, 1/50-1/100 and 1/20, respectively.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/1842_C4_62_selected.jpg
Subcellular Location
Figure 2 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/ihc_selected.jpg
Subcellular Location
Figure 3 IHC staining of human blood vessel
Immunohistochemical staining of human blood vessel shows distinct positivity of plasma.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5036/ihc_selected.jpg
Normal Tissue
Figure 4 Immunofluorescent staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/395_F9_1_red_green.jpg
Normal Tissue
Figure 5 Immunofluorescent staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/399_F9_1_red_green.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5036/14071_A_8_4.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HDLM-2, U-2 OS, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132693-CRP
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CRP
- Species Reactivity
- Human
- Clone
- R09-9G4
- Applications
- WB, IHC-P, IP
- Related Disease
- Appendicitis; Meningitis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IP: 1/20
Target
- Alternative Names
- PTX1
- Gene ID
- 1401
- UniProt ID
- P02741
- Long Name
- C-reactive protein
- Cellular Localization
- Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P02741)
Modification sites at neXtProt (NX_P02741)
- Protein Refseq
- NP_000558.2; NP_001315986.1
- Function
- Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-0214-FY-S(P) | Mouse Anti-CRP Recombinant Antibody scFv Fragment (HPAB-0214-FY-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-M0039-YC-S(P) | Mouse Anti-CRP Recombinant Antibody (clone P24); scFv Fragment | ELISA | Mouse scFv |
| HPAB-M0040-YC-S(P) | Mouse Anti-CRP Recombinant Antibody (clone P03); scFv Fragment | ELISA | Mouse scFv |
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| VS-0525-XY1678 | Anti-Human CRP Immunohistochemistry Kit | IHC |
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