CytoStream™ Mouse Anti-CRTC1 Recombinant Antibody (VS13-YC250) (CAT#: VS13-YC250)
The CytoStream™ Mouse Anti-CRTC1 Recombinant Antibody is specific for human CRTC1. CRTC1 regulates transcription in contexts like cancer, influencing signaling pathways through protein interactions affecting cellular growth and maintenance. The anti-CRTC1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nuclear bodies, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/187_C10_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nuclear bodies, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/187_C10_1_selected.jpg
Figure 2 Cerebellum
(High expression in cerebellum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_B_7_8_val_selected.jpg
(High expression in cerebellum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_B_7_8_val_selected.jpg
Figure 3 Testis
(Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_A_4_6.jpg
(Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_A_4_6.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_B_8_5.jpg
(Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_B_8_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_A_9_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_A_9_3.jpg
Figure 6 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22035/48988_A_7_4.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105662-CRTC1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105662-CRTC1
Specifications
- Immunogen
- Recombinant human Torc1 protein expressed in E.coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human CRTC1
- Species Reactivity
- Human
- Applications
- WB, ICC, IF, IP, FC
- Conjugate
- NONE
- Related Disease
- Mucoepidermoid Carcinoma and Clear Cell Hidradenoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/20
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- CREB Regulated Transcription Coactivator 1; Mucoepidermoid Carcinoma Translocated Protein 1; TORC-1; WAMTP1; MECT1; TORC1; Transducer Of Regulated CAMP Response Element-Binding Protein (CREB) 1;
- Gene ID
- 23373
- UniProt ID
- Q6UUV9
- Long Name
- CREB Regulated Transcription Coactivator 1
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| MOR-0813 | Hi-Affi™ Rabbit Anti-CRTC1 Recombinant Antibody (clone DS813AB) | IHC-P, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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