Mouse Anti-CSF2RB Recombinant Antibody (VS3-FY2677)
CAT#: VS3-FY2677
This anti-CSF2RB antibody is a mouse recombinant monoclonal antibody that is specifically created to bind CD131. The calculated molecular weight of the antigen is 97.3 kDa. It cross-reacts with human, mouse and rat. This monoclonal antibody is potential for conducting research on Surfactant Metabolism Dysfunction, Pulmonary, 5 and Hereditary Pulmonary Alveolar Proteinosis. This monoclonal antibody can be used in Western Blot, Immunohistochemistry, Flow cytometry, ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HUVEC TERT2
Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78677/1751_C10_13_cr57fd269edaa96_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HEL, HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100368-CSF2RB
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Colony stimulating factor 2 receptor beta common subunit of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC, FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 97.3 kDa.
- Related Disease
- Surfactant Metabolism Dysfunction, Pulmonary, 5 and Hereditary Pulmonary Alveolar Proteinosis
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Colony Stimulating Factor 2 Receptor Beta Common Subunit; Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage); GM-CSF/IL-3/IL-5 Receptor Common Beta Subunit; Beta Common Cytokine Receptor; Beta-GM-CSF Receptor; CDw131; IL3RB; IL5RB; Interleukin 3 Receptor/Granulocyte-Macrophage Colony Stimulating Factor 3 Receptor, Beta (High Affinity)
- Gene ID
- 1439
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 4 subfamily.
- Cellular Localization
- Membrane; Single-pass type I membrane protein
- Post Translation Modifications
- May be phosphorylated by LYN.
Glycosylation at Asn58, Asn191, and Asn346
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites
- Protein Refseq
- XP_011528205.1; XP_011528206.1; XP_047297104.1; XP_047297105.1; XP_047297106.1
- Function
- Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA (PubMed:1495999).
In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "CSF2RB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABZ-029 | Mouse Anti-CSF2RB Recombinant Antibody (clone BION-1) | Block, IP | Mouse IgG |
| MOB-0205CT | Recombinant Mouse anti-Human CSF2RB Monoclonal antibody (2D2) | FC | |
| VS4-WK127 | Human Anti-CSF2RB Recombinant Antibody (clone 7B6) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-029 | Mouse Anti-CSF2RB Recombinant Antibody (clone BION-1); Fab Fragment | Block, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-029 | Mouse Anti-CSF2RB Recombinant Antibody (clone BION-1); scFv Fragment | Block, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0827 | Hi-Affi™ Rabbit Anti-CSF2RB Recombinant Antibody (clone DS827AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC378 | Recombinant Anti-CSF2RB Vesicular Antibody, EV Displayed (VS-0425-YC378) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1709 | Anti-CSF2RB Immunohistochemistry Kit | IHC |
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