Mouse Anti-CSPG4 Recombinant Antibody (clone 2164H5/E11) (CAT#: HPAB-645-FY)

It is a recombinant mouse antibody that is designed to target CSPG4. It originates from a hybridoma cell line. The antibody specifically identifies segments of NG2/CSPG4 isoforms that are shed from the cellular surface and dispersed within the vascular basement membrane (VBM) and extracellular matrix (ECM).


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Inhib

Figure 1 Shows the effects on cell migration of the antibodies (hybridoma clones 2172B12/C10, 2166G4/C10/D1, 2164H5/E11, 2161D2/C2 and their subclonal derivations).

Figure 1 Shows the effects on cell migration of the antibodies (hybridoma clones 2172B12/C10, 2166G4/C10/D1, 2164H5/E11, 2161D2/C2 and their subclonal derivations).

Cyt

Figure 2 Shows apoptosis measured by multiparametric assay induced by administering the antibodies (hybridoma clones2164H5/E11, 2161D2/C2 and their subclonal derivations) on HT1080NG2+ cell lines.

Figure 2 Shows apoptosis measured by multiparametric assay induced by administering the antibodies (hybridoma clones2164H5/E11, 2161D2/C2 and their subclonal derivations) on HT1080NG2+ cell lines.

Activ

Figure 3 Shows activation of caspases responsible for propagation of the extrinsic apoptotic pathway after administration of the antibodies (hybridoma clones 2164H5/E11, 2161D2/C2 and their subclonal derivations) in the model cancer cell lines (A375).

Figure 3 Shows activation of caspases responsible for propagation of the extrinsic apoptotic pathway after administration of the antibodies (hybridoma clones 2164H5/E11, 2161D2/C2 and their subclonal derivations) in the model cancer cell lines (A375).

Activ

Figure 4 Shows activation of caspases responsible for propagation of the extrinsic apoptotic pathway after administration of the antibodies (hybridoma clones 2164H5/E11, 2161D2/C2 and their subclonal derivations) in the model cancer cell lines (A376).

Figure 4 Shows activation of caspases responsible for propagation of the extrinsic apoptotic pathway after administration of the antibodies (hybridoma clones 2164H5/E11, 2161D2/C2 and their subclonal derivations) in the model cancer cell lines (A376).


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human CSPG4
  • Species Reactivity
  • Human
  • Clone
  • 2164H5/E11
  • Applications
  • FC, ELISA
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The CSPG4 antibody has been reported in applications of Inhibition, Cytotoxicity, Activation.

Target

  • Alternative Names
  • Chondroitin Sulfate Proteoglycan 4; Melanoma-Associated Chondroitin Sulfate Proteoglycan; Chondroitin Sulfate Proteoglycan 4 (Melanoma-Associated); Melanoma Chondroitin Sulfate Proteoglycan; Chondroitin Sulfate Proteoglycan NG2; MCSP; MEL-CSPG;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 2164H5/E11"

See other products for "CSPG4"

Immunotoxin

CAT Product Name Application Type
AGTO-G013E Anti-CSPG4 immunotoxin (scFv)-PE Cytotoxicity assay, Function study
AGTO-G013S Anti-CSPG4 immunotoxin (scFv)-Sap Cytotoxicity assay, Function study
AGTO-G014E Anti-CSPG4 immunotoxin (IgG)-PE Cytotoxicity assay, Function study
AGTO-G014S Anti-CSPG4 immunotoxin (IgG)-Sap Cytotoxicity assay, Function study

Blocking Antibody

CAT Product Name Application Type
NEUT-550CQ Mouse Anti-CSPG4 Recombinant Antibody (clone 9.2.27) EM, Block, IP, FC, ICC, IF Mouse IgG2a

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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