Afuco™ Anti-CTLA4 ADCC Recombinant Antibody (Ticilimumab (= Tremelimumab)), ADCC Enhanced (CAT#: AFC-TAB-206)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CTLA4. Tremelimumab (formerly ticilimumab, CP-675,206) is a fully human IgG2 monoclonal antibody, undergoing human trials for the treatment of cancer.
Host: Human
Isotype: ADCC enhanced antibody
Applications: IF, IP, Neut, FuncS, ELISA
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
Specifications
- Immunogen
- Human CTLA-4.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Ticilimumab (= Tremelimumab)
- Applications
- IF, IP, Neut, FuncS, ELISA
- Conjugate
- Unconjugated
- Generic Name
- Ticilimumab (= Tremelimumab)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Ticilimumab (= tremelimumab); 745013-59-6; ticilimumab; CP-675; 206; Ticilimumab; CP-675; 206; CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease 3, CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28; CD152; GSE; ICOS; CD152 isoform; celiac disease 3;
- Gene ID
- 1493
- UniProt ID
- P16410
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Ticilimumab (= tremelimumab)"
Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab))Recombinant monoclonal antibody to CTLA4. Tremelimumab (formerly ticilimumab, CP-675,206) is a fully human IgG2 monoclonal antibody, undergoing human trials for the treatment of cancer.
See other products for "CTLA4"
Human Antibody
| CAT | Product Name | Application | Type |
| TAB-067 | Anti-Human CTLA4 Recombinant Antibody (Ipilimumab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-206 | Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab)) | WB, IF, IP, Neut, FuncS, ELISA, FC | IgG2 |
Immunotoxin
| CAT | Product Name | Application | Type |
| AGTO-G015E | Anti-CTLA4 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G015S | Anti-CTLA4 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study | |
| AGTO-G015M | Anti-CTLA4 immunotoxin (scFv)-Mel | Cytotoxicity assay, Function study |
Rat Antibody
| CAT | Product Name | Application | Type |
| TAB-195CL | Mouse Anti-CTLA4 Recombinant Antibody (TAB-195CL) | ELISA | Mouse IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
| TAB-083MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.H) | ELISA, FC | Humanized antibody |
| TAB-084MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2422.H) | ELISA, FC | Humanized antibody |
| TAB-088MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-088MZ) | ELISA | Human IgG |
| TAB-091MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-091MZ) | ELISA | Human IgG1 |
| TAB-092MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-092MZ) | ELISA | Human IgG1 |
Chimeric Antibody
| CAT | Product Name | Application | Type |
| TAB-085MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-085MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-086MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-085MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-086MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
| TAB-087MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-087MZ) | ELISA | Mouse IgG |
| TAB-089MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-089MZ) | ELISA | Mouse IgG1 |
| TAB-090MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-090MZ) | ELISA | Mouse IgG1 |
| TAB-093MZ | Anti-Human CTLA4 Recombinant Antibody (Mu-26B) | ELISA | |
| TAB-087MZ-F(E) | Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-087MZ-F(E)) | ELISA | Mouse Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
| NEUT-567CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone 14D3) | FC, FuncS, Neut, IP, WB | Mouse IgG2a, κ |
| NEUT-569CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone AS32) | WB, Neut | Mouse IgG1 |
| NEUT-570CQ | Human Anti-CTLA4 Recombinant Antibody (clone YC030) | Neut | Human IgG1, κ |
| NEUT-572CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4B9) | FC, Block, ELISA, IP | Hamster IgG |
| NEUT-573CQ | Rat Anti-Ctla4 Recombinant Antibody (clone 63828) | WB, FC, Neut | Rat IgG2a |
Blocking Antibody
| CAT | Product Name | Application | Type |
| NEUT-568CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone L3D10) | FC, Block | Mouse IgG1, κ |
| NEUT-571CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone BN13) | Block, FC | Mouse IgG2a |
| NEUT-577CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone MAB0835) | Block, FC | Hamster IgG |
| NEUT-578CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone RYNmCTLA-4) | Block | Hamster IgG |
| NEUT-581CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4F10-11) | Block, FC, WB | Hamster IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
| MOR-0855 | Hi-Affi™ Rabbit Anti-CTLA4 Recombinant Antibody (clone DS855AB) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
| HPAB-0749LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0749LY) | FuncS, ELISA | Human IgG |
| HPAB-0750LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0750LY) | FuncS, ELISA | Human IgG |
| HPAB-0751LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0751LY) | FuncS, ELISA | Human IgG |
| HPAB-0752LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0752LY) | FuncS, ELISA | Human IgG |
| HPAB-1660LY | Mouse Anti-CTLA4 Recombinant Antibody (HPAB-1660LY) | FC, Block, ELISA | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-0749LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0749LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0750LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0750LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0751LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0751LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0752LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0752LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0753LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0753LY-F(E)) | FuncS, ELISA | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-610-FY-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-610-FY-S(P)) | ELISA | Human scFv |
| HPAB-611-FY-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-611-FY-S(P)) | ELISA | Human scFv |
| HPAB-0219-WJ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0219-WJ-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0220-WJ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0220-WJ-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-S0013-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody (clone 6.1.1); scFv Fragment | ELISA, Block | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
| AFC-TAB-067 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody (Ipilimumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
Single-domain Antibody
| CAT | Product Name | Application | Type |
| HPAB-AP860-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP860-YC) | ELISA, Block | Camel VHH |
| HPAB-AP861-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP861-YC) | ELISA, Block | Camel VHH |
| HPAB-AP862-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP862-YC) | ELISA, Block | Camel VHH |
| HPAB-AP863-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP863-YC) | ELISA, Block | Camel VHH |
| HPAB-AP864-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP864-YC) | ELISA, Block | Camel VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
WBWestern Blot
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