Human Anti-CTLA4 Recombinant Antibody (clone E8); scFv Fragment (CAT#: HPAB-M0045-YC-S(P))
Provided are fully human antibodies that bind CTLA4. Stimulation is achieved using antibodies that block binding of human CTLA4 to human B7 and diseases amenable to treatment by stimulation and augmentation of prolonging of immune responses include cancers of the prostate, kidney, colon, lung or breast.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human CTLA4
- Species Reactivity
- Human
- Clone
- E8
- Applications
- ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cytotoxic T-Lymphocyte Associated Protein 4; Insulin-Dependent Diabetes Mellitus 12; Celiac Disease 3; CTLA-4; CD152; Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4; Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form; Cytotoxic T-Lymphocyte-Associated Serine Esterase-4; Cytotoxic T-Lymphocyte-Associated Antigen 4; Cytotoxic T-Lymphocyte Protein 4;
- Gene ID
- 1493
- UniProt ID
- P16410
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-986 | Recombinant Mouse Anti-Human CTLA4 Antibody F(ab')2 Fragment, clone ANC152.2/8H5 | FC, EIA, FX, Bios | F(ab')2 |
| DrMAB-987 | Mouse Anti-CTLA4 Recombinant Antibody (clone ANC152.2/8H5); Fab Fragment | FC, ELISA | Mouse Fab |
| HPAB-0051-YC-F(E) | Human Anti-CTLA4 Recombinant Antibody (clone 10D1); Fab Fragment | ELISA, Cyt, Block | Human Fab |
| HPAB-0157-FY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0157-FY-F(E)) | Activ | Humanized Fab |
| HPAB-N0343-YC-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-N0343-YC-F(E)) | FC, ELISA | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-067 | Anti-Human CTLA4 Recombinant Antibody (Ipilimumab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-206 | Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab)) | WB, IF, IP, Neut, FuncS, ELISA, FC | IgG2 |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G015E | Anti-CTLA4 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G015S | Anti-CTLA4 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study | |
| AGTO-G015M | Anti-CTLA4 immunotoxin (scFv)-Mel | Cytotoxicity assay, Function study |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-195CL | Mouse Anti-CTLA4 Recombinant Antibody (TAB-195CL) | ELISA | Mouse IgG |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-085MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-085MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-086MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-085MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-086MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-087MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-087MZ) | ELISA | Mouse IgG |
| TAB-087MZ-F(E) | Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-087MZ-F(E)) | ELISA | Mouse Fab |
| TAB-089MZ-F(E) | Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-089MZ-F(E)) | ELISA | Mouse Fab |
| TAB-090MZ-F(E) | Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-090MZ-F(E)) | ELISA | Mouse Fab |
| TAB-093MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (Mu-26B) | ELISA |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-083MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.H) | ELISA, FC | Humanized antibody |
| TAB-084MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.H) | ELISA, FC | Humanized antibody |
| TAB-088MZ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-088MZ-S(P)) | ELISA | Human scFv |
| TAB-091MZ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-091MZ-S(P)) | ELISA | Human scFv |
| TAB-092MZ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-092MZ-S(P)) | ELISA | Human scFv |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-567CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone 14D3) | FC, FuncS, Neut, IP, WB | Mouse IgG2a, κ |
| NEUT-569CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone AS32) | WB, Neut | Mouse IgG1 |
| NEUT-570CQ | Human Anti-CTLA4 Recombinant Antibody (clone YC030) | Neut | Human IgG1, κ |
| NEUT-572CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4B9) | FC, Block, ELISA, IP | Hamster IgG |
| NEUT-573CQ | Rat Anti-Ctla4 Recombinant Antibody (clone 63828) | WB, FC, Neut | Rat IgG2a |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-568CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone L3D10) | FC, Block | Mouse IgG1, κ |
| NEUT-571CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone BN13) | Block, FC | Mouse IgG2a |
| NEUT-577CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone MAB0835) | Block, FC | Hamster IgG |
| NEUT-578CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone RYNmCTLA-4) | Block | Hamster IgG |
| NEUT-579CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone 9H10) | FC, Block | Hamster IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0855 | Hi-Affi™ Rabbit Anti-CTLA4 Recombinant Antibody (clone DS855AB) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0157-FY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0157-FY) | Activ | Humanized IgG1, κ |
| HPAB-0749LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0749LY) | FuncS, ELISA | Human IgG |
| HPAB-0750LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0750LY) | FuncS, ELISA | Human IgG |
| HPAB-0751LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0751LY) | FuncS, ELISA | Human IgG |
| HPAB-0752LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0752LY) | FuncS, ELISA | Human IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-067 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody (Ipilimumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-206 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody (Ticilimumab (= Tremelimumab)), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0054-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody (clone 4H9-G5-D5-B1); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-1270WJ-S(P) | Mouse Anti-CTLA4 Recombinant Antibody (clone 26); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-1271WJ-S(P) | Human Anti-CTLA4 Recombinant Antibody (clone h26); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-1302WJ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-1302WJ-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-1303WJ-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-1303WJ-S(P)) | ELISA, WB, FC | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP860-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP860-YC) | ELISA, Block | Camel VHH |
| HPAB-AP861-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP861-YC) | ELISA, Block | Camel VHH |
| HPAB-AP862-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP862-YC) | ELISA, Block | Camel VHH |
| HPAB-AP863-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP863-YC) | ELISA, Block | Camel VHH |
| HPAB-AP864-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP864-YC) | ELISA, Block | Camel VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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